Red blood cell partitioning and blood flux redistribution in microvascular bifurcation  

作　　者：Yuanqing Xu Fangbao Tian Hanjun Li Yulin Deng 

机构地区：[1]School of Life Science, Beijing Institute of Technology, Beijing 100081, China [2]Department-of Mechanical Engineering, Vanderbilt University, 2301 Vanderbilt Place, Nashville,Tennessee 37235-1592, USA

出　　处：《Theoretical & Applied Mechanics Letters》2012年第2期76-80,共5页力学快报（英文版）

基　　金：supported by Excellent Young Teachers Program (3160012261-001);Fund for Basic Research(3160012211104) of Beijing Institute of Technology;partly supported by the National Key Technology R&D Program (2009BAK59B01)

摘　　要：This paper studies red blood cell （RBC） partitioning and blood flux redistribution in microvascular bifurcation by immersed boundary and lattice Boltzmann method. The effects of the initial position of RBC at low Reynolds number regime on the RBC deformation, RBC partitioning, blood flux redistribution and pressure distribution are discussed in detail. It is shown that the blood flux in the daughter branches and the initial position of RBC are important for RBC partitioning. RBC tends to enter the higher-flux-rate branch if the initial position of RBC is near the center of the mother vessel. The RBC may enter the lower-flux-rate branch if it is located near the wall of mother vessel on the lower-flux-rate branch side. Moreover, the blood flux is redistributed when an RBC presents in the daughter branch. Such redistribution is caused by the pressure distribution and reduces the superiority of RBC entering the same branch. The results obtained in the present work may provide a physical insight into the understanding of RBC partitioning and blood flux redistribution in microvascular bifurcation.This paper studies red blood cell （RBC） partitioning and blood flux redistribution in microvascular bifurcation by immersed boundary and lattice Boltzmann method. The effects of the initial position of RBC at low Reynolds number regime on the RBC deformation, RBC partitioning, blood flux redistribution and pressure distribution are discussed in detail. It is shown that the blood flux in the daughter branches and the initial position of RBC are important for RBC partitioning. RBC tends to enter the higher-flux-rate branch if the initial position of RBC is near the center of the mother vessel. The RBC may enter the lower-flux-rate branch if it is located near the wall of mother vessel on the lower-flux-rate branch side. Moreover, the blood flux is redistributed when an RBC presents in the daughter branch. Such redistribution is caused by the pressure distribution and reduces the superiority of RBC entering the same branch. The results obtained in the present work may provide a physical insight into the understanding of RBC partitioning and blood flux redistribution in microvascular bifurcation.

关 键 词：immersed boundary lattice Boltzmann method red blood cell microvascular bifurcation 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] F124.7[自动化与计算机技术—控制科学与工程]