妊娠期高血压疾病患者围产儿不良结局与脐动脉血流的关系探讨  

Study on correlation between adverse outcome hypertension disorder complicating pregnancy and umbilical artery flow of fetus

作　　者：王志明[1] 庄如锦[2] 韩聪慧 袁宏伟 陈素芬[1] 乔素贞[1] 解雅春[1] 付智伟[1] 郭琳[1] 宗禹希[2] 张慧颖[1] 

机构地区：[1]哈尔滨医科大学公共卫生学院儿少卫生与妇幼保健教研室,黑龙江哈尔滨150081 [2]哈尔滨医科大学附属第二医院妇产科,黑龙江哈尔滨150086 [3]哈尔滨市红十字中心医院,黑龙江哈尔滨150010 [4]牡丹江市妇幼保健院,黑龙江牡丹江157000

出　　处：《中国儿童保健杂志》2012年第3期218-220,共3页Chinese Journal of Child Health Care

基　　金：国家自然科学基金(30771818;81172682)

摘　　要：【目的】研究妊娠期高血压疾病(hypertension disorder complicating pregnancy,HDCP)对围产儿结局的影响及胎儿脐动脉血流变化与围产儿不良结局的关系。【方法】对57例妊娠期高血压疾病孕产妇和59例正常妊娠孕产妇的妊娠结局进行观察,测量胎儿脐动脉血流指标并观察两组围产儿结局。【结果】HDCP组围产儿的不良结局在新生儿窒息、早产和低出生体重方面的发生率均高于正常组(P<0.05);两组在脐动脉血流搏动指数(PI)、阻力指数(RI)、收缩压最大血流速度与舒张末期最大血流速度比值(S/D)等三个指标上存在的差异有统计学意义(P<0.05)。胎儿脐动脉血流指标与围产儿出生结局呈负相关关系。【结论】HDCP患者更容易发生围产儿不良结局,胎儿脐动脉血流指标更易出现异常。脐动脉血流指标RI和S/D比值可以用来预测围产儿不良结局的发生。【Objective】To study the impact of hypertension disorder complicating pregnancy（HDCP） on pregnancy outcome and to investigate the relationship between index of umbilical artery blood flow and pregnancy adverse outcomes.【Method】A prospective survey of 57 HDCP patients and 59 normal pregnant women were selected,the perinatal outcomes were observed,and the index of fetal growth and umbilical artery blood flow were recorded.【Results】In the incidence rates of neonate asphyxia,premature labor,fetal low birth weight,and the index of umbilical artery blood flow,HDCP group were significantly higher than those of normal group（P0.05）.Between umbilical artery blood flow and pregnancy outcomes,there was a significant negative correlation.【Conclusions】Adverse pregnancy outcomes and abnormal umbilical artery blood flow indices are more likely to appear in HDCP mothers.Indices of uterine artery flow can predict the occur of adverse pregnancy outcomes.

关 键 词：妊娠期高血压 围产儿结局 脐动脉血流 

分 类 号：R722.1[医药卫生—儿科]