天然黄酮类化合物清除自由基机理及其应用进展  

Flavonoids' Mechanism of Scavenging Free Radicals and its Application as Natural Antioxidants

作　　者：孟庆华[1] 于晓霞[1] 张海凤[2] 张绍良 

机构地区：[1]上海交通大学化学化工学院,上海200240 [2]上海中医药大学中药学院,上海201203 [3]青龙高科技股份有限公司,江西宜春336000

出　　处：《云南民族大学学报（自然科学版）》2012年第2期79-83,共5页Journal of Yunnan Minzu University:Natural Sciences Edition

基　　金：上海市科委纳米专项资助项目(0752nm016)

摘　　要：黄酮类化合物在植物资源中具有广泛的分布,其清除自由基作用使其可用作天然抗氧剂.介绍了机体内自由基形成以及抗氧剂清除自由基的机理,讨论了黄酮化合物的化学结构特征和其清除自由基的构效关系.在应用方面,天然黄酮化合物具有广谱的清除自由基药理作用,还可用在食品的抗氧化领域和化妆品的清除自由基、紫外吸收等方面.Flavonoids, a kind of natural antioxidants, have become popular for their wide application. The mechanism of scavenging free radicals and the structure - activity relationship were discussed. The medical effects and the application as pharmaceuticals, food addictives and cosmetics were summarized.

关 键 词：黄酮 自由基 抗氧剂 

分 类 号：R282.7[医药卫生—中药学] TQ65[医药卫生—中医学]