旱莲草对酪氨酸酶激活作用的动力学研究  

Kinetics for activation of herba ecliptae on tyrosine

作　　者：徐秋[1] 吴可克[1] 陈丽凤[1] 刘建峰 刘伟 

机构地区：[1]大连轻工业学院化学工程系,辽宁大连116034

出　　处：《大连轻工业学院学报》2000年第1期25-27,共3页Journal of Dalian Institute of Light Industry

摘　　要：酪氨酸酶是黑素生物合成途径中的主要限速酶 ,旱莲草有促进酪氨酸酶活性的作用。通过对旱莲草的水提液和乙醇提取液促进酪氨酸酶活性作用的观察研究及旱莲草提高酪氨酸酶活性的动力学观察研究 ,得到lineweaver burk曲线、动力学回归方程及米氏Km值。为进一步研究中药有效成分能使白发变黑的分子机理奠定了基础。Tyrosine is a major enzyme which controls the speed of producing black coloring material. Herba ecliptae has the function of stimulating the activity of tyrosine. In the experiment, line Weaver-Burk curve, Km value, and kinetic regression equation have been obtained by analyzing herba ecliptae's water extract and alcohol extract which speed up tyrosine's activity, and by kinetic studying of the activity increasing of tyrosine. This will afford the foundation for further study on the mechanism of turning white hair into black hair.

关 键 词：旱莲草 酪氨酸酶 激活作用 动力学 提取液 

分 类 号：R282.71[医药卫生—中药学] R284.2[医药卫生—中医学]