长春西汀注射液的过敏性、溶血性和血管刺激性的实验研究  

The clinical trial of the hemolysis,vasculay initation and sensirivation of vinpocetine injection

作　　者：陈颖丽[1] 张殿文[1] 王清[1] 李伟[1] 

机构地区：[1]吉林省中医药科学院,长春130012

出　　处：《中国实用医药》2012年第3期7-9,共3页China Practical Medicine

摘　　要：目的研究长春西汀注射液的溶血性、血管刺激性和过敏反应,为其临床用药的安全性提供科学依据。方法按照《化学药物刺激性、过敏性和溶血性研究技术指导原则》的要求,对长春西汀注射液进行了溶血性、血管刺激性和过敏反应实验研究。结果动物实验表明,长春西汀注射液无溶血作用、无血管刺激性及致敏作用。结论长春西汀注射液在0.3 mg/ml浓度时,无溶血作用、无血管刺激性及致敏作用。Objective To provide the scientific basis for Vinpocetine injection as clinical trial,the hemolytic reaction,vascular irritation and sensitization of this injection were studied.Methods Hemolysis,vascular irritation and sensitization experiments were performed under Vinpocetine injection according to 《Principles and Methods of studies for Chemical induced irritation,sensitization and hemolysis》.Results Vinpocetine injection has no effects of hemolysis,vascular irritation or sensitization.Conclusion Vinpocetine injection has no effects of hemolysis,vascular irritation or sensitization at the concentration of 0.3 mg/ml.

关 键 词：长春西汀注射液 溶血性 血管刺激性 过敏反应 

分 类 号：R96[医药卫生—药理学]