急性ST段抬高型广泛前壁心肌梗死急诊与择期PCI术血浆NT-proBNP变化的临床观察  

Clinical observation to plasma NT-proBNP of the patients with STEMI

作　　者：景舒南[1] 赖碁[1] 杨芳[1] 彭春花[1] 方杰[1] 

机构地区：[1]昆明医学院附属延安医院,云南昆明650051

出　　处：《中外医学研究》2012年第7期1-2,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨急性ST段抬高型广泛前壁心肌梗死(ST elevation myocardial,STAMI)急诊与择期PCI术前后血浆N氨基酸末端脑钠肽前体(NT-proBNP)的变化。方法:72例急性ST段抬高型广泛前壁心肌梗死根据发病时间分为急诊PCI组37例与择期PCI组35例。分别于入院24h内或急诊经皮冠状动脉介入术(PCI)前及术后第6天检测血浆NT-proBNP。结果:直接PCI组与择期PCI组治疗前后比较,血浆NT-proBNP明显下降(P<0.05)。直接PCI组与择期PCI组之间治疗前后比较,差异无统计学意义(P>0.05)。结论:急性ST段抬高型广泛前壁心肌梗死急诊和择期PCI术前后,血浆NT-proBNP均明显下降。PCI术对于患者的远期预后均有不同程度的益处。Objective： To explore the relationship between the changes of plasma N - terminal pro - B - type natriuretic peptide （ NT - proBNP） in early acute myocardial infarction（STEMI）. Methods：Seventy -two patients admitted to our hospital with AMI were randomly divid- ed into two groups ,35 were the the elective PCI group and another 37 were the temergent PCI group. The plasma NT - proBNP was measured within 24 hours after admission or before PCI and on the 6th day after postoperative. Results ：The levels of plasma NT -proBNP decreased after the treatment in both of the two groups than that before treatment significantly （P 〈 0.05）, and no significant difference were observed fo the te- mergent PCI group and the elective PCI group （ P 〉 0.05 ）. Conclusion ：The emergent PCI and the elective PCI may make the plasma NT - proB- NP to decrease significantly and to be beneficial for the Acute myocardial infarction.

关 键 词：急性心肌梗死 血浆N氨基末端脑鈉肽前体 经皮冠状动脉介入术 

分 类 号：R542.22[医药卫生—心血管疾病]