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机构地区:[1]贵阳医学院医学检验系,贵阳550004 [2]贵阳医学院寄生虫学教研室,贵阳550004
出 处:《中国寄生虫学与寄生虫病杂志》2012年第1期73-75,共3页Chinese Journal of Parasitology and Parasitic Diseases
基 金:国家自然科学基金(No.30660168)~~
摘 要:将4头20日龄三元杂交乳猪感染猪带绦虫虫卵,8×10^4个/头,感染后第40、80、120和150天采集有囊尾蚴寄生的肝、肌肉和脑组织,制备病理切片,观察囊尾蚴发育过程中周围组织的病理反应。结果显示,感染第40~80天,肝脏内寄生的囊尾蚴被宿主纤维结缔组织增生形成的外膜包围,与肝组织交界处有大量炎症细胞浸润;感染第120天,大部分囊尾蚴出现死亡或钙化;感染第150天,囊尾蚴已全部死亡或钙化。感染第40天,寄生于骨骼肌和舌肌的囊尾蚴周围有炎症细胞浸润,邻近头节的肌纤维炎症反应较囊壁其余部位严重;感染第80~150天,囊尾蚴周围炎症细胞浸润呈带状分布。心肌的病理反应与骨骼肌和舌肌相似.但浸润的炎症细胞稍多。感染第40天。寄生于脑组织的囊尾蚴周围有少量炎症细胞浸润,感染第80~150天,囊尾蚴周围有大量炎症细胞浸润,形成炎症带。猪囊尾蚴寄生的周围组织的炎症反应随感染时间延长逐渐加强,且肝脏的炎症反应强于肌肉和脑组织的反应。Four three-way crossed hybrid pigs were infected each with 80 000 Taenia solium eggs. One pig was sacrificed respectively at 40, 80, 120, and 150 d post-infection, and tissue samples containing cysticerci were collected for pathological sections. The results showed that in 40-80 days, cysticerci in the liver were surrounded by membrane formed with the hyperplastic fibrous connective tissue and inflammatory cells. On 120th day, a large number of the cysticerci were dead or calcified. On 150th day, all cysticerci died or calcified. On 40th day, the inflammatory cells infil- trated around the cysticerci in the tongue and skeletal muscle, and the inflammatory responses near the scolex were more serious than that near cyst wall. In the 80-150 days, the inflammatory cells showed bandlike distribution. The pathological response in cardiac muscle was similar to that of the skeletal muscle and the tongue, but with more inflammatory cells. On 40th day, there were a few inflammatory cells infiltrating around cysticerci in the brain, in the 80-150 days, a large number of inflammatory cells aggregated around the cysticerci. The inflammatory response in the tissues progressed with the duration of infection and the inflammation in the liver was significantly stronger than that in other tissues.
分 类 号:R383.321[医药卫生—医学寄生虫学]
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