和谐及企图和谐异常视网膜对应共同性内斜视患者生活质量和心理状况的临床研究  

Vision related quality of life and emotional impact in concomitant esotropic patients with harmonious anomalous retinal correspondence

作　　者：邵毅[1] 裴重刚[1] 周琼[1] 刘新华[1] 余瑶 董雯佳[1] 常以力[1] 谭钢[3] 王华[4] 高桂平[1] 

机构地区：[1]南昌大学第一附属医院眼科,江西省南昌市330006 [2]南昌市第三医院内分泌科,江西省南昌市330009 [3]南华大学附属第一医院眼科,湖南省衡阳市421001 [4]中南大学湘雅医院眼科,湖南省长沙市410008

出　　处：《眼科新进展》2012年第3期230-232,共3页Recent Advances in Ophthalmology

基　　金：国家自然科学基金(编号:81160118;81100648;81170823;81100649;81160105);江西省科技计划项目(编号:20111BBG70026-2);广东省高校优秀青年创新人才培养计划(编号:LYM10112);江西省卫生厅科研基金资助项目(编号:20121026)~~

摘　　要：目的评价和谐及企图和谐异常视网膜对应共同性内斜视患者生活质量和心理状况,分析斜视手术对其影响。方法通过前瞻性随机临床对照的方法,对和谐及企图和谐异常视网膜对应共同性内斜视患者36例分别采用《国家眼科研究视功能问卷》和《综合医院焦虑抑郁量表》中文译本评定患者最近1个月的视觉生活质量和焦虑、抑郁评分,手术后1个月再次评定患者焦虑、抑郁情况及视觉生活质量,36例健康志愿者作为对照,比较两组患者生活质量和心理状况的差异。结果和谐及企图和谐异常视网膜对应共同性内斜视患者焦虑、抑郁及共患患者发生率分别为22.2%、25.0%、27.8%。《国家眼科研究视功能问卷》评分显示术前共同性内斜视患者在视觉健康相关生活质量部分亚功能(7/12)如一般健康、总体视觉、驾驶、社会功能、心理问题、周边视野和依赖性等均有不同程度的损害(均为P<0.05)。通过斜视手术干预,患者视觉生活质量和心理状态均有明显好转(均为P<0.05)。通过斜视手术干预,患者焦虑、抑郁评分明显好转(均为P<0.05),视觉健康相关生活质量的样本中位数差值[43.3(一般健康)、38.2(社会功能)、12.4(心理问题)、17.5(社会活动)、16.4(依赖性)、12.4(周边视野)],均较手术前明显改善[8.6(一般健康)、7.3(社会功能)、3.5(心理问题)、3.6(社会活动)、2.8(依赖性)、5.6(周边视野),均为P<0.05]。结论斜视手术可使和谐及企图和谐异常视网膜对应共同性内斜视患者心理状况和视觉健康相关生活质量得到明显改善。斜视手术有助于患者视觉生活质量和心理康复。Objective To evaluate the vision related quality of life（VRQOL） and emotional impact in concomitant esotropic patients with anomalous retinal correspondence（ARC） and harmonious anomalous retinal correspondence（H-ARC）,and investigate its changes by surgery interventions.Methods This prospective random control study included 36 concomitant esotropic patients with ARC and H-ARC.A healthy control group（36 cases） matched to the group was established.The VRQOL and anxiety and depression symptoms scoring were evaluated and analyzed on the preoperative and postoperative one month by two instruments.Instruments applied included the NEI-VFQ-25 and Hospital Anxiety and Depression Scale（HADS）.The difference of VRQOL and emotional impact between two groups was compared.Results The incidence of anxiety,depression,anxiety and depression in concomitant esotropic patients were 22.2%,25.0%,27.8%,respectively.Compared with control subjects,concomitant esotropic patients showed significantly impaired disease-specific VRQOL in 7 out of 12 subscales,including general health,general vision,social functioning,mental problems,peripheral vision,driving and dependency（P0.05）.Compared with preoperative values,significant improvements were noted after surgery in NEI-VFQ summary score,anxiety and depression scores（all P0.05）.The VRQOL of concomitant esotropic patients had been improved at 1 month after second surgery compared with those of pre-surgery（all P0.05）.Conclusion The VRQOL and emotional impact in concomitant esotropic patients with ARC and H-ARC are improved by surgery interventions,the surgery can promote the recovery of VRQOL and emotion.

关 键 词：异常视网膜对应 共同性内斜视 眼科手术 问卷调查 

分 类 号：R49[医药卫生—康复医学]