老年人肾功能测定方法的评价  

Evaluation of Applicability of Renal Function Estimating Methods in Elderly Patients

作　　者：孟瑚[1] 罗惠民[1] 

机构地区：[1]云南省第一人民医院肾内科,昆明650032

出　　处：《医学综述》2012年第4期581-583,共3页Medical Recapitulate

摘　　要：对于老年人,精确地评估肾小球滤过率对明确慢性肾脏病、早期实施保护肾功能的治疗、并给予正确的药物剂量至关重要。临床常用的评估肾功能的方法有血清肌酐、内生肌酐清除率,根据CG公式或MDRD公式估算肾小球滤过率,血清胱抑素C和放射性核素法,还有近年出现的基于血清胱抑素C的估算公式。这些方法在老年人群中的应用各有不足之处。临床需根据实际条件和对诊断精确度的要求,选择合适的方法。Accurate glomerular filtration rate measurement is important for identification of chronic renal disease which may allow early implementation of renoprotective therapy and proper medication dosing among elderly individuals.Current detection methods consist of serum creatinine concentration,endogenous creatinine clearance ratea,ccording to CG formula or MDRD formula estimate glomerular filtration rate,serum cystatin C concentration,radioisotopic methods,and the formula based on cystatin C.Each of them has inadequacy in elderly population.In clinical practice,it is necessary to choose a suitable methods according to available armamentarium and requirement.

关 键 词：肾小球滤过率 老年 肌酐 血清胱抑素C 

分 类 号：R692.6[医药卫生—泌尿科学]