心室重构相关生化标志物的研究进展  

Research Progress of Ventricular Remodeling Related Biochemical Markers

作　　者：李艳[1] 马依彤[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,乌鲁木齐830054

出　　处：《医学综述》2012年第5期656-658,共3页Medical Recapitulate

基　　金：新疆维吾尔自治区自然科学基金(2010211A44)

摘　　要：心室重构是导致冠心病、心肌病等进行性发展,引起恶性心律失常、心力衰竭甚至心源性猝死的重要因素。其进展过程中伴随的相关生化标志物改变可帮助临床医师及早识别无临床症状患者心室重构的发生,并为处于不同疾病阶段的患者提供积极的个体化治疗方案,对延缓心室重构的进展,改善患者的预后发挥着不可估量的作用。近年来,与心室重构相关的生化标志物的研究是心血管最为活跃的研究领域之一,并取得了丰硕成果。现对近年来心室重构相关生化标志物的研究进展予以综述。Ventricular remodeling is an important factor leading to coronary heart disease, cardiomyopathy progress, and malignant arrhythmia, heart failure and even sudden death. The biochemical markers along with ventricular remodeling may help to identify patients with no clinical evidence of ventricular remodeling, and provide customized aggressive therapy for patients at different stages of the disease. It also plays an immeasurable role of delaying the progress of ventricular remodeling and improving the prognosis of patients. In recent years, research of ventricular remodeling related biochemical markers is the most active cardiovascular research field and have made great achievements. Here is to make a review on the recent literature on these biochemical markers.

关 键 词：心室重构 生化标志物 基质金属蛋白酶 组织抑制因子 磺基转移酶2 心肌营养素1 

分 类 号：R542[医药卫生—心血管疾病]