三黄泻心汤三种制备方式样品中盐酸小檗碱和黄芩苷含量比较  

Comparison of the Contents of Berberine and Baicalin in Three Preparation Methods for San huang Xiexin Decoction

作　　者：蒋品[1] 高言明[1] 梁光义[1] 贺祝英[2] 李健[1] 聂雨霁[1] 刘莉[1] 梁婷[1] 

机构地区：[1]贵阳中医学院,贵州贵阳550002 [2]贵阳中医学院第一附属医院,贵州贵阳550001

出　　处：《辽宁中医杂志》2012年第3期514-516,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(30860364)

摘　　要：目的:考察三黄泻心汤传统汤剂、复方浸膏和配方浸膏中盐酸小檗碱和黄芩苷的含量差异。方法:采用HPLC法测定其中的盐酸小檗碱、黄芩苷的含量。结果:配方浸膏中盐酸小檗碱、黄芩苷含量远远大于传统汤剂和复方浸膏中盐酸小檗碱、黄芩苷的含量。结论:从化学成分角度分析,配方浸膏中盐酸小檗碱、黄芩苷含量较传统汤剂和复方浸膏存在明显差异,可为临床应用提供科学依据。Objective ： To study the contents difference of berberine hydrochloride and baicalin in decoction, compound extract and mixed extract of San huang Xiexin decoction. Methods ： The contents of berberine hydrochloride and baicalin in three forms of the sample solution determined by HPLC. Results：The contents of berberine hydrochloride and baiealin in mixed extract are the highest of all. Conclusion ： From the point of view of chemical composition, the contents of berberine hydrochloride and baicalin in the three forms of the sample were respectively different and can be used to provide theoretical basis on its clinical application.

关 键 词：三黄泻心汤传统汤剂 复方浸膏 配方浸膏 盐酸小檗碱 黄芩苷 

分 类 号：R284.2[医药卫生—中药学]