厄贝沙坦/氢氯噻嗪治疗老年高血压的疗效及安全性观察  

The efficacy and safety of Irbesartan/Hydrochlorothiazide treatment of hypertension in the elderly

作　　者：王珊波 

机构地区：[1]浙江省宁波市鄞州区古林社区卫生服务中心,宁波315157

出　　处：《海峡药学》2012年第2期76-77,共2页Strait Pharmaceutical Journal

摘　　要：目的探讨厄贝沙坦/氢氯噻嗪复方片(商品名:安博诺)治疗老年高血压的疗效及安全性。方法对60例轻中度老年高血压患者应用安博诺治疗24周,观察其降压疗效和不良反应。结果安博诺服药4周、8周、12周、24周后患者SBP和DBP显著下降(P<0.01),降压总有效率达90.0%,血压达标率85.0%;治疗前后电解质、尿酸、肾功能、血糖、血脂比较差异无统计学意义(P>0.05),无明显不良反应。结论安博诺治疗老年高血压安全、有效。OBJECYIVE To investigate the efficacy and safety of Irbesartan/Hydrochlorothiazide compound tablets （brand name：Ember＇s） in treatment of hypertension in the elderly.METHODS 60 patients with mild to moderate hypertensive patients with senile Ember＇s treatment for 24 weeks, to observe its antihypertensive effica cy and adverse reactions. RESULTS Compared with before treatment, SBPand DBP had fallen significantly in 4, 8, 12 and 24 weeks（P 〈 0.05）. Ember＇s buck total effective rate was 90.0 %, blood pressure compliance rate was 85.0 %. There were no changes in electrolyte, uric acid, renal function, blood sugar and lipid （ P 〉 0.05）. There was no obvious adverse reactions. CONCLUSION Ember＇s is safe and effective in treatment of senile hyperten sion .

关 键 词：厄贝沙坦 氢氯噻嗪 安博诺 高血压 

分 类 号：R969.4[医药卫生—药理学]