用于电刺激的植入式铂黑微电极(英文)  

Implantable Pt-Black Coated Microelectrode for Electrical Stimulation

作　　者：芮岳峰[1,2,3] 刘景全[1,2,3] 杨春生[1,2,3] 

机构地区：[1]上海交通大学微米/纳米加工技术国家级重点实验室,上海200240 [2]上海交通大学薄膜与微细加工教育部重点实验室,上海200240 [3]上海交通大学微纳科学技术研究院,上海200240

出　　处：《纳米技术与精密工程》2012年第2期103-107,共5页Nanotechnology and Precision Engineering

基　　金：supported by the National Natural Science Foundation of China(60876082);the Science and Technology De-partment of Shanghai(0852nm06600);the Program for New Cen-tury Excellent Talents in University(2009);the"Shu Guang" project supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation(08SG13);Aviation Science Foundation(2008ZE57019)~~

摘　　要：传统的植入式电刺激微电极表面积小,电极/组织界面阻抗高,并且电荷存储容量(CSC)小,这些都会增加植入式系统的功耗并影响电刺激效果.提出了一种在电极点电镀铂黑的方法来增加微电极的有效面积(ESA).通过在超声波浴下使用脉冲电流电镀的方法,可以极大地增加微电极的ESA,降低界面阻抗并增加CSC和电荷注入容量.铂黑微电极的几何特性和电学特性分别由扫描电子显微镜(SEM)和电化学分析仪测定,并与未镀铂黑的电极特性进行了对比,对铂黑镀层的机械稳定性也做了相应的测试.实验结果表明,铂黑镀层的纳米结构使铂黑电极相比普通铂电极界面阻抗降低了1/16,CSC扩大13倍.在5 min的室温超声波衰减实验中,阴极电荷存储容量(CSCC)仅减小20%.Conventional implantable electrical stimulation microelectrodes have small surface area, high electrode-tissue interface impedance and low charge storage capacity （ CSC ）, which will increase power consumption and hinder stimulation effect. In this paper, a method was presented to increase the effective surface area（ESA） of microelectrode by coating Pt-black on the electrode sites. The method combines with electroplating Pt-black by pulse current under ultrasonic bath, which can significantly increase the ESA, decrease the interface impedance, and increase the CSC and charge-injection capacity. Moreover, the geometrical properties of Pt-black coated microelectrodes were demonstrated by using a scanning elec- tron microscope（SEM） and the electrical properties were measured by an electrochemical analyzer com- pared with conventional microelectrodes without coatings. The mechanical stability of Pt-black coating was also tested. Experimental results show that approximately 16 times lower interface impedance and 13 times higher CSC were achieved by this nanostructured microelectrode. Cathodal charge storage capacity （ CSCc ） decreased only by 20% after an ultrasonic bath at room temperature for 5 min.

关 键 词：生物医学工程 派瑞林 微电极 植入式 铂黑 

分 类 号：R318.0[医药卫生—生物医学工程]