吡咯并[2,1,5-cd]中氮茚酰腙衍生物的合成及Cu^(2+)荧光探针行为  

Synthesis of 3-Phenyl-pyrrolo[2,1,5-cd]indolizine-1-carboxylic acid(2-hydroxy-benzylidene)-hydrazide and Its Application as Fluorescent Sensors for Cu^(2+)

作　　者：杨安博[1] 王炳祥[1] 

机构地区：[1]江苏省生物功能材料重点实验室江苏省生物医药功能材料工程研究中心南京师范大学化学与材料科学学院,南京210097

出　　处：《高等学校化学学报》2012年第3期492-495,共4页Chemical Journal of Chinese Universities

基　　金：江苏省自然科学基金(批准号:BK2008435);江苏省高校优势学科建设工程项目资助

摘　　要：设计合成了吡咯并[2,1,5-cd]中氮茚酰腙衍生物6.测试了其紫外光谱和荧光光谱,研究了其对铜离子的选择性识别作用.结果表明,化合物6作为铜离子荧光探针,受常见离子干扰较小,对于铜离子有着较高的选择性和较低的检出限.3-Phenyl-pyrrolo[2,1,5-cd]indolizine-1-carboxylic acid（2-hydroxy-benzylidene）-hydrazide（6） was synthesized and used as fluorescent sensors for Cu2＋ ion.The structure of the compound 6 was determined by IR,1H NMR,MS and elemental analysis and their UV and fluorescence spectra were measured.The influences of ten metal ions such as Cu2＋,Zn2＋,Ni2＋,Co2＋,Al3＋,Cr3＋,Mn2＋,Na＋,Sn2＋ and Ca2＋ on their fluorescence properties were studied.Spectroscopic studies revealed that the compound 6 had rather strong affinity toward Cu2＋.The specificity of the probe 6 toward Cu2＋ was determined.Nearly no fluorescence intensity changes were observed in emission spectra with Zn2＋,Ca2＋,Na＋,K＋,Cr3＋,Sn2＋,Al3＋ but Ni2＋ and Co2＋.However,under identical conditions,the results showed fluorescence quenching with Cu2＋.So we have developed a new fluorescent sensor 6.It shows high sensitivity and selectivity toward Cu2＋ in DMSO.

关 键 词：吡咯并[2 1 5-cd]中氮茚酰腙衍生物 铜离子 荧光探针 

分 类 号：O626.21[理学—有机化学]