榆树根皮的化学成分(Ⅲ)  

Chemical constituents of root bark of Ulmus pumila(Ⅲ)

作　　者：王东[1] 夏明钰[2] 姜楠 代英辉[1] 辛妤[1] 崔征[1] 

机构地区：[1]沈阳药科大学中药学院,辽宁沈阳110016 [2]沈阳药科大学生命科学与生物制药学院,辽宁沈阳110016 [3]丹东市元宝区卫生监督和预防保健中心,辽宁丹东118000

出　　处：《沈阳药科大学学报》2012年第3期190-192,共3页Journal of Shenyang Pharmaceutical University

摘　　要：目的研究榆树(Ulmus pumila L.)根皮中的化学成分。方法采用反复硅胶柱色谱法,凝胶柱色谱法,半制备HPLC等进行分离纯化;通过理化常数测定和光谱分析鉴定其化学结构。结果从榆树根皮正丁醇提取物中分离得到了6个化合物,即lyoniside(1)、(+)-lyoniresinol 3α-O-α-L-rh-amnopyranoside(2)、正丁基-O-β-D-吡喃果糖苷(n-butyl-O-β-D-fructopyranoside,3)、正丁基-O-α-D-呋喃果糖苷(n-butyl-O-α-D-fructofuranoside,4)、正丁基-O-β-D-呋喃果糖苷(n-butyl-O-β-D-fructo-furanoside,5)、胡萝卜苷(daucosterol,6)。结论化合物2-5为属内首次分离得到,化合物1为种内首次分离得到。Objective To study the chemical constituents of the root bark of Ulmus pumila L. Methods The compounds were isolated by chromatography on silica gel column, Sephadex LH-20 gel column and semipreparative HPLC. The structures of these compounds were identified on the basis of physicochemical constants and spectral analysis. Results Six compounds were isolated and identified as lyoniside（ 1 ）, （ ＋ ） -lyoniresinol 3a-O-α-L-rhamnopyranoside （ 2 ）, n-butyl-O-β-D-fructopyranoside （ 3 ）, n-butyl-O-α-D-fructofuranoside （4）, n-butyl-O-β-D-fructofuranoside （ 5 ） and daucosterol （ 6 ）. Conclusions Compounds 2-5 are isolated from the Ulmus for the first time and compound 1 is isolated from this plant for the first time.

关 键 词：榆科 榆树 根皮 化学成分 

分 类 号：R284[医药卫生—中药学]