急性心肌梗死不同梗死部位与冠脉病变血管血浆hs-CRP和Hcy变化的临床观察  

Clinical observation to different locations of AMI and hs-CRP and Hcy in plasma

作　　者：景舒南[1] 赖碁[1] 杨芳[1] 彭春花[1] 方杰[1] 

机构地区：[1]昆明医学院附属延安医院,650051

出　　处：《中国医学创新》2012年第6期15-16,共2页Medical Innovation of China

摘　　要：目的探讨急性ST段抬高型心肌梗死(STEMI)不同梗死部位和冠脉病变血管血浆hs-CRP、Hcy的变化。方法 69例急性心肌梗死患者根据心电图、心肌坏死标记物及冠脉造影分为急性ST段抬高广泛前壁心肌梗死组37例和急下壁心肌梗死组32例。于发病24h内抽取静脉血行血浆hs-CRP、Hcy检测。结果急性ST段抬高广泛前壁和下壁心肌梗死早期血浆hs-CRP和Hcy均高于正常值,且广泛前壁心肌梗死组的hs-CRP和Hcy要高于下壁心肌梗死组,但两组比较差异无统计学意义(P>0.05)。结论 hs-CRP和Hcy是急性心肌梗死的危险因素,并且可反映心肌损害和血管病变的程度。Objective To explore the relationship between the different locations of acute myocardial infarction with elevated ST segment（STEMI） as well as coronary narrowing and the levels of high-sensitive C-reactive protein（hs-CRP） and hemoeysteine（Hcy） in plasma.Methods Sixty-nine patients of STMI were divided into group-1（n=37, the infarction was located in the wide anterior wall） and group-2（n=32, the infarction was located in the inferior wall） by ECG and coronary angiogram. The hs-CRP and Hcy in plasma were tested for all of the patients with venous blood samples taken within 24 hours of the AMI.Results The hs-CRP and Hcy was elevated over the normal level significantly in both of the two groups（P〈0.05）. That was higher in group-1 than that of group-2 but the difference was not significant（P〉0.05）.Conclusion Both hs-CRP and Hcy are risk factors of AMI and may reflect the extent of the myocardial injury and coronary narrowing.

关 键 词：急性心肌梗死 冠状动脉狭窄 高敏C-反应蛋白 同型半胱氨酸 

分 类 号：R542.22[医药卫生—心血管疾病]