用于血管性皮肤病治疗的固体激光技术概述  

Development of All-Solid-State Medical Laser for Skin Vascular Dermatosis

作　　者：田玉冰 檀慧明 崔锦江 王帆 施燕博 董宁宁 

机构地区：[1]苏州生物医学工程技术研究所,江苏苏州215163

出　　处：《激光与光电子学进展》2012年第3期24-33,共10页Laser & Optoelectronics Progress

基　　金：江苏省自然科学基金面上项目(BK2010235);苏州市应用基础研究计划项目(SYG201127);苏州医工所青年引导基金项目(Y052051205)资助课题

摘　　要：激光疗法是治疗血管性皮肤病最为便捷和可靠的方案。介绍了激光治疗血管性皮肤病的选择吸收原理及氧合血红蛋白的吸收峰位置,从而确定了激光波长的选择依据,阐述了418、542、577nm波段医用全固体激光器的相关技术及发展现状,重点阐述了医用577nm波段的5种激光技术:倍频、和频、受激拉曼散射(SRS)、光参量振荡器(OPO)及光抽运半导体(OPS)技术。指出了各种技术的优缺点及其医用前景。在和频技术中,提出了将薄片结构与端抽运结构相结合的新型医用578nm黄光激光器的设计方案。The treatment of skin vascular disease with all-solid-state laser is a safe, effective and successful option. We review literatures on the laser technique for treatment of skin vascular disease. The absorption peak of oxyhemoglobin and the selective absorption principle of tissue are introduced. The main techniques for generating 418, 542 and 577 nm laser are discussed. The yellow 577 nm medical laser techniques including frequency doubling, sum frequency mixing, stimulated Raman scattering （SRS）, optical parametric oscillator （OPO）and optically pumped semiconductor （OPS） are emphasized. The advantages and the development trend of different ways are pointed out. In the discussion of sum frequency mixing, the new scheme to produce 578 nm laser by employing thin disc and end- pumping configuration is demonstrated.

关 键 词：激光器 全固态激光器 氧合血红蛋白 和频 倍频 光抽运半导体技术 

分 类 号：TN248.1[电子电信—物理电子学]