右室高位间隔部与心尖部VVI起搏对心功能的影响  

The effect of lead at right high-interventricular septum and right ventricular apex on cardiac function in patients implanted with VVI permanent pacemakers.

作　　者：陈乔[1] 傅春江[1] 杨立[1] 于长青[1] 王伟[1] 王旭开[1] 

机构地区：[1]第三军医大学大坪医院野战外科研究所心血管内科重庆市心血管病研究所,重庆400042

出　　处：《中国心脏起搏与心电生理杂志》2012年第1期39-40,共2页Chinese Journal of Cardiac Pacing and Electrophysiology

摘　　要：目的探讨高位间隔部(HRVS)与心尖部(RVA)起搏对心功能的影响。方法行VVI起搏并愿随访的患者104例,其中HRVS起搏54例,RVA起搏50例,分别于术前及术后1周、半年、1年及3年在同一起搏频率下(60次/分)用超声心动图测定左室射血分数(LVEF)、左室短轴缩短率、心输出量和监测脑钠肽(BNP)水平。结果HRVS起搏患者LVEF及BNP水平无明显改变;RVA起搏患者LVEF(术后半年、3年分别为0.60±0.15、0.54±0.16)降低及BNP(术后半年、3年分别为96.51±46.41 ng/L、168.33±49.37 ng/L)水平升高。结论 VVI HRVS起搏优于RVA起搏。Objective To determine the effect of lead at right high-interventricular septum （RHVS） and right ventricu- lar apex （RVA）on cardiac function. Method One hundred and four cases with 3-year follow-up, implanted with VVI permanent pacemakers, including 54 cases of lead at RHVS and 50 cases of lead at RVA. The cardiac function was meas- ured with the same pacing frequency （60 bpm） at 1 week, 6 months, 1 year and 3 years post-implantation. Left ventricular ejection fraction （LVEF） , fractional shortening, cardiac output were measured with echocardiogram and brain natriuretic peptide （BNP） was also measured. Results Lead at RHVS did not significantly affect LVEP and BNP; Lead at the RVA deteriorates cardiac funT,tion （ LVEF decereased： 0.60 ±0.15,0.54 ±0.16 at 6 months and 3 years, BNP increased： 96. 51 ±46.41 ng/l., 168.33± 49.37 ng/L at 6 months and 3 years）. Conclusion Pacing at RHVS is superior to pacing at RVA.

关 键 词：心血管病学 高位间隔部起搏 心尖部起搏 心功能 左室射血分数 脑钠肽 

分 类 号：R318.11[医药卫生—生物医学工程]