苦参不同提取液对慢性湿疹治疗效果的研究  

Study on Clinical Effect of Chronic Eczema Treating with Different Extraction Solvents from Sophora flavescens

作　　者：吴伟明[1] 孙忠敏[1] 陈丽佳[1] 黄田艺 

机构地区：[1]温州医学院附属第二医院,浙江温州325027 [2]浙江慈爱康复医院,浙江杭州310012

出　　处：《中华中医药学刊》2012年第3期650-652,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:研究苦参不同提取液对慢性湿疹临床治疗的效果。方法:选择患有慢性湿疹的病人150例,随机分为5组,4个治疗组使用苦参的不同提取液和不同给药方式进行临床治疗,对照组给予西替利嗪口服,观察临床治疗效果及不良反应等情况。结果:4个治疗组相对于对照组疗效较好,具有显著意义(P<0.05);其中使用SBE提取液外用方法对湿疹患者治疗时治疗效果最好,苦参外用会导致四肢麻痹的不良反应,而苦参内服会出现胃肠道的反应。结论:治疗效果是将SBE提取液外用最好,可以减轻皮肤瘙痒,不会出现胃肠道的反应,且见效快。Objective： Extraction Solvents from Sophora flavescens were observed on its effect on chronic eczema. Methods ： 150 cases of chronic eczema were chosen and randomly divided into five groups. The four treatment groups took modified different extraction Solvents from Sophora flavescens and manners of administration, and the control group took cctirizine orally. The therapeutic effects and complications were observed after treatment. Results： The clinical efficacy of the four treatment groups was superior to the control group （ P 〈 0.05 ）. The best treatment was topical application with SBE extraction of Solvents. Topical Sophora flavescens would caused limb paralysis side effects, and oral administration of Sophora flavescens would occured gastrointestinal reactions. Conclusion： The best treatment was topical application with SBE extraction of Solvents, which can reduce skin itching, and gastrointestinal reactions would not occur, with fast effect.

关 键 词：苦参 慢性湿疹 治疗效果 

分 类 号：R758.23[医药卫生—皮肤病学与性病学]