铜纳米粒子的可控制备及其抗菌性能研究  

Controllable preparation and antibacterial activity of copper nanoparticles

作　　者：陈丹[1] 徐晓玲[1] 段惺[1] 范希梅[1] 周祚万[1] 

机构地区：[1]西南交通大学材料科学与工程学院,材料先进技术教育部重点实验室,四川成都610031

出　　处：《功能材料》2012年第6期803-805,共3页Journal of Functional Materials

基　　金：国家高技术研究发展计划(863计划)资助项目(2009AA03Z27);航天CAST基金资助项目(20091001SWJTU01)

摘　　要：以氯化铜为铜源,水合肼为还原剂,十六烷基三甲基溴化铵(CTAB)为稳定剂,氨水为络合剂,通过液相还原法合成了纳米铜粉。通过改变还原剂浓度制备了4组不同粒径纳米铜粉末,FESEM等表征发现,随着水合肼浓度的降低,纳米铜粉粒径增加。通过肉汤稀释振荡培养法测试纳米铜的最小抑菌浓度,结果表明,随着纳米铜粒径的增加,抗菌性能降低,所合成纳米铜的最小抑菌浓度在750～3000mg/L;初步分析认为铜纳米粒子主要是通过水解或电离出铜离子而发挥抗菌作用。The copper nanoparticles were prepared through aqueous chemical reduction method with copper chloride as the copper source, hydrazine as the reductant, cetyl trimithyl ammonium bromide as the stabilizer, am monia water as the complexant. The results indicate that with the concentration of hydrazine decresed, the particle size of the obtained copper nanoparticles increased. The MIC values of the samples are measured to be 750 3000mg/L by broth dilution method. The studies also showed that the smaller the size of the copper particle is, the higher the antibacterial activity display. Copper ions through hydrolysis or ionization may be responsible for antibacterial properties.

关 键 词：纳米铜 抗菌 水合肼 

分 类 号：TB34[一般工业技术—材料科学与工程]