抗癫痫新药瑞替加滨  

Retigabine:a new agent for epileptic treatment

作　　者：王丹[1] 高颖[1] 刘婷立[1] 王晓旭[1] 薛烨[1] 

机构地区：[1]沈阳亿灵医药科技有限公司,沈阳110179

出　　处：《中国新药杂志》2012年第5期467-469,共3页Chinese Journal of New Drugs

摘　　要：瑞替加滨为神经元钾离子通道开放剂,是一种具有全新作用机制的抗癫痫药,临床上用于成人癫痫部分发作的辅助治疗。文中对瑞替加滨的作用机制、药效学、药代动力学、药物相互作用、临床评价和安全性等进行综述。Retigabine is a neuronal potassium channel opener.Retigabine is a new antiepileptic drug for adjunctive treatment of partial-onset seizures in adult patients with a novel mechanism of action.The mechanism,pharmacodynamics,pharmacokinetics,drug interaction,clinical evaluation,and safety of retigabine were reviewed.

关 键 词：瑞替加滨 癫痫 钾离子通道开放剂 

分 类 号：R971.43[医药卫生—药品]