基于超分子环糊精两亲分子的敏感型囊泡体系  

Sensitive Vesicle System Based on Supramolecular Cyclodextrin Amphiphiles

作　　者：辛飞飞[1] 张华承[1] 孙涛[1] 孔丽[1] 李月明[1] 郝爱友[1] 

机构地区：[1]山东大学化学与化工学院,济南250100

出　　处：《化学进展》2012年第2期414-422,共9页Progress in Chemistry

摘　　要：敏感型囊泡可初步概括为由两亲分子通过非共价键构筑的、对外界的刺激具有特色响应性的一类新型囊泡体系。由"超分子环糊精两亲分子"自组装形成的囊泡体系是该类体系中重要的一类。本文重点介绍了环糊精参与的"超分子环糊精两亲分子"囊泡体系的研究进展。以与环糊精复合的化合物结构类型不同进行分类,介绍了该类囊泡体系的制备以及该体系在医药工程、新型"智能"材料以及生物模拟等方面的潜在应用;结合现阶段的研究状况,对该类囊泡体系的发展前景进行了展望。Sensitive vesicle system, which is formed by amphiphiles constructed non-covalently has unique responsiveness to external stimuli. Vesicles prepared from ＂ surpamolecular cyclodextrin amphiphiles （SCA）are one of the most important types. Here, the development of this kind of vesicular system is reviewed. At first, the preparation and applications in pharmaceutical engineering, new smart materials, biological mimics, etc. of this kind of vesicle system classified by the guest molecules are introduced and described. Then the prospects are pointed out based on the current development of the system.

关 键 词：环糊精 超分子环糊精两亲分子 自组装 敏感囊泡 

分 类 号：O636.12[理学—高分子化学] O641.3[理学—化学]