基于矩阵分析法的慢性萎缩性胃炎辨证论治疗效评价研究  

Comparison on String-Like Pulse Figure Parameters between Hypertension and Non-Hypertension Cases

作　　者：宇文亚[1] 李周利[2] 沈舒文[3] 郭丽媛[3] 刘力[3] 杨志宏[3] 惠建萍[3] 

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]西安石油大学电子工程学院,西安710065 [3]陕西中医学院附属医院,咸阳712000

出　　处：《世界科学技术-中医药现代化》2012年第1期1266-1269,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金项目(30873266):基于慢性萎缩性胃炎癌前病变虚实关联证候辨治的临床疗效评价方法研究;负责人:沈舒文

摘　　要：目的：探索矩阵分析法在中医辨证论治疗效评价中的应用。方法：以慢性萎缩性胃炎（CAG）为范例,临床选择经＂虚实标本证候辨识数据库＂辨识的CAG 5种虚实相兼证候共100例,采用补虚泻实、标本兼治的证治方法治疗,半年为一疗程,疗程结束后采用证候矩阵、治疗矩阵、效果矩阵模型的变量测算及误差矩阵推导,推算出疗效值。结果：虚实标本辨治慢性萎缩性胃炎总体症状的疗效为0.4~0.6,具有统计学意义（P〈0.05）。结论：初步表明矩阵分析法可用于中医辨证论治的疗效评价。This study was aimed to analyze pulse with time-domain analysis method in the comparison of string-like pulse figure parameters between hypertension and non-hypertension cases.The hemodynamics changes and formation mechanism between two kinds of string-like pulses were also initially inferred.The string-like pulse figure of 224 primary hypertension cases and 300 non-hypertension cases were collected and compared with the ZBOX-1 Pulse Condition Instrument.The time-domain parameters（h3/h1,h4/h1,w/t） were compared for hypertension string-like pulse and non-hypertension string-like pulse.The result showed that the h3/h1 value of string-like pulse of both hypertension and non-hypertension group is significantly higher than the healthy group（P0.01）;and the h3/h1 value of hypertension group is significantly higher than non-hypertension group（P0.01）;the h4/h1 value of hypertension group is significantly higher than non-hypertension and healthy groups（P0.01）;the w/t value of both hypertension and non-hypertension group are significantly higher than the healthy group（P0.01）.It was concluded that the string-like pulse group of hypertension has high peripheral resistance,poor blood vessel elasticity and increased arterial tension.The string-like pulse group of non-hypertension has no significant changes in peripheral resistance.But the arterial compliance in non-hypertension group has been decreased.The main arteries are at high pressure and high tension status.Both of them have different blood dynamics basis.

关 键 词：矩阵分析法 慢性萎缩性胃炎 辨证论治 疗效评价 

分 类 号：R259.733.2[医药卫生—中西医结合]