细菌性肝脓肿影响因素分析  

Risk factors analysis of pyogenic hepatic abscess:A case-control study

作　　者：刘坤[1,2] 林斌[1,2] 汪启乐 马垚[1,2] 

机构地区：[1]徐州医学院附属宿迁医院 [2]南京鼓楼医院集团宿迁市人民医院肝胆外科,宿迁223800

出　　处：《肝胆外科杂志》2012年第1期40-42,共3页Journal of Hepatobiliary Surgery

摘　　要：目的探讨细菌性肝脓肿(pyogenic hepatic abscess,PHA)的患病风险。方法采用1∶1配对的病例对照研究,对31对病例及对照组相关9个危险因素进行条件Logistic回归分析。结果单因素分显示DM(OR=6.328,95%CI:1.787～22.409)、胆道疾病(OR=8.759,95%CI:1.006～76.097)和恶性肿瘤史(OR=4.444,95%CI:0.467～42.258)是PHA的可能风险因素(均P<0.20);多因素Logistic回归分析显示DM(OR=7.747,95%CI:1.975～28.275)是PHA的风险因素(P=0.003)。结论 DM患者患PHA的风险是非DM患者的7.75倍,提高对DM增加PHA患病风险的认识,早期诊治可能会改善预后。Objective To study the risk factory of pyogenic hepatic abscess （PHA）. Methods 1 ： 1 matched case - control study was conducted on 31 pairs of cases using the condition Logistic regression analysis on 9 related risk factors. Results The univariate analysis revealed that DM （ OR = 6. 328,95 % CI ： 1. 787 - 22. 409 ）, biliary tract disease （ OR = 8. 759,95 % CI ： 1. 006 - 76. 097 ） and history of malignancy（OR =4. 444,95% CI：0. 467-42. 258） is possible risk factors of PHA（P 〈0.20） ;multi-factor Logistic Regression analysis showed that DM （ OR = 7. 747,95 % CI ： 1. 975 - 28. 275 ） is a risk factor of PHA （ P = 0. 003 ）. Conclusion The risk of DM patients suffering from PHA as 7.75 times as non-DM, enhancement awareness of the risk, early diagnosis and treatment may improve prognosis.

关 键 词：糖尿病 细菌性肝脓肿 病例对照研究 LOGISTIC回归分析 

分 类 号：R657.33[医药卫生—外科学]