MIJ和HFJ近交系大鼠心电图表现  

Characterization of typical ECG of inbred MIJ and HFJ rats

作　　者：陈贵良[1,2] 刘军须[1] 陈则永[2] 蔡月花[1] 曹福源[2] 高丽萍[2] 刘福英[1] 

机构地区：[1]河北医科大学河北省实验动物重点实验室,石家庄050017 [2]河北联合大学,河北唐山063000

出　　处：《中国实验动物学报》2012年第1期55-59,共5页Acta Laboratorium Animalis Scientia Sinica

基　　金：河北省科技支撑计划重点项目(编号:09276426D)

摘　　要：目的测定近交系MIJ、HFJ大鼠心电图,并与Wistar大鼠比较分析,观察MIJ和HFJ大鼠心电图表现。方法大鼠麻醉后,仰卧位固定于大鼠固定板上,用短针电极刺入皮下2～3 mm位置,麻醉5 min后,用福田青岛FX-102B心电图机做心电图,并对心电图进行分析。结果三种大鼠均为窦性心律,心律齐整,雄性HFJ、MIJ心率均高于同性别Wistar。HFJ和MIJ品系、性别间心率差异均无显著性。HFJ和MIJ心电轴与Wistar相同,主要在0°～90°间。三种大鼠的P波方向及QRS波群基本相同,但各波振幅和各波时限,在不同品系和性别之间存在较明显的差异。结论近交系MIJ和HFJ大鼠各有其独特的心电图表现。Objective To observe the typical ECG appearance of the inbred MIJ and HFJ rats and compare with that of Wistar rats. Methods Six of each gender and strains of rats were selected as one group. The rats were anesthetized and fixed on a board. A needle electrode pierced into the skin about 2-3 ram. FX-IO2B ECG device was applied to perform the ECG record. Results As same as that of Wistar rats, both the male and female MIJ and HFJ rats showed a sinus rhythm, and the heart rhythm was regular. No marked differences were showed between the genders and the MIJ and HFJ rats. However, compared with the male Wistar rats, the heart rate of male HFJ and MIJ rats was higher. The electrical axis of heart in HFJ and MIJ rats was as the same as that of the Wistar rats, mostly ranging from 0°-90°. All characteristics of P-waves and QRS waves in the HFJ and MIJ rats were the same as that of Wistar rats. But there were apparent differences in the amplitude and periods of different waves between the strains and genders. Conclusion There are characteristic ECG manifestations in inbred MIJ and HFJ rats.

关 键 词：HFJ和MIJ近交系大鼠 心电图 特征 观察 

分 类 号：Q95-33[生物学—动物学]