羟胺及烷氧基胺盐酸盐绿色生产工艺探索及实践  

The Analysis and Study on Green Synthesis of Hydroxylamine and O-alkyl Hydroxylamine Hydrochloride

作　　者：王伟 林勇 张胜建[3] 张洪[3] 

机构地区：[1]宁波工业投资集团有限公司,浙江宁波315000 [2]宁波欧迅化学新材料技术有限公司,浙江宁波315203 [3]浙江大学宁波理工学院,浙江宁波315100

出　　处：《山东化工》2012年第2期1-4,共4页Shandong Chemical Industry

摘　　要：对羟胺及烷氧基胺盐酸盐生产工艺进行了分析比较,提出了一条酮氨氧化制备酮肟-酮肟醚化-水解制备烷氧基胺盐酸盐及回用酮这样一条绿色生产工艺路线。此工艺操作条件温和,原子经济性高,收率好。以丙酮、氯甲烷为主要原料制备甲氧基胺盐酸盐,总收率可达84.6%,原子经济性达48.0%。The synthetic processes of hydroxylamine and O - alkyl hydroxylamine hydrochloride were analysed, and a new green synthesis mute, through ammonia oxidation, O - alkylation, hydrolysis in HC1 from ketone was advanced. This process had mild operating conditions, high atomic economy, and better yield. For example, the yield of O -methyl hydroxylamine hydrochloride from acetone and methyl chloride achieved 84.6%, and the atomic economy got 48.0%.

关 键 词：酮 酮肟 羟胺盐酸盐 烷氧胺盐酸盐 绿色化学 

分 类 号：TQ217[化学工程—有机化工]