林蛙油冲剂对超重环境下微波辐射大鼠的抗氧化效应研究  

The Research of Rana Japonica Oil Compound Prescription Powder about Big Mouse Oxidation Resistance Effect which Under the Overweight Environment and Microwave Radiation

作　　者：王芸芸[1] 李春卉[1] 潘文干[1] 曹慧玲[1] 吕士杰 沈楠[1] 

机构地区：[1]吉林医药学院,吉林吉林132015

出　　处：《中国辐射卫生》2012年第1期6-7,共2页Chinese Journal of Radiological Health

基　　金：吉林省教育厅"十一五"科技研究项目(项目编号:2009315)

摘　　要：目的探究不同剂量的长白山特产林蛙油冲剂,对超重环境下微波辐射大鼠的抗氧化效应,为林蛙油的开发研究提供依据。方法用Wistar大鼠复制超重环境和微波辐射协同作用的动物模型,用高、中、低三种剂量的林蛙油冲剂和角鲨烯进行干预,检测各组大鼠血清总抗氧化能力、超氧化物歧化酶活性、丙二醛含量和抑制羟自由基的能力进行分析。结果低剂量林蛙油组的总抗氧化能力显著高于其他5组;超重辐射组的丙二醛含量显著高于其他5组、抑制羟自由基能力也高于其他5组。结论按大鼠每天每1 000g体重40mg林蛙油(干重)配制的低剂量复方冲剂的抗氧化效应,明显优于其他剂量的林蛙油冲剂和角鲨烯胶囊。Objective To explore the suppression function of healthy products mainly made from rana japonica oil of different dosage configuration compound prescription powder grown in the Changbai Mountain on oxidation resistance effect of the big mice which have been under the condition of overload and radiation. Methods The models of wister big mice under overload and radiation were established and intervened with the healthy products made from rana japonica oil and squalene, the ability of total oxidation resistance,superoxide dismutase,maleic dialdehyde and the hydroxyl free radical in the serum taken from ead group of big mice was examined. Results The total oxidation resistance ability＇s activeness of low dose rana japonica oil line is obviously higher than that of other 5 groups. The ability of the overload radiation group＇s maleic dialdehyde is obviously higher,the hydroxy free radical is higher these of other 5 groups. Conclusion Every day 40 mg rana japonica oil configuration low dose compound prescription powder per Rilogiam of body weight perday for big mice its oxidation resistance effect obviously surpasses other dosage of the rana japonica oil compound prescription powder and the squalene capsule.

关 键 词：超重环境 微波辐射 林蛙油 抗氧化作用 

分 类 号：Q441[生物学—生理学]