短波紫外线与氦氖激光照射对感染性伤口愈合影响的研究  

Research on treatment of infected wound by ultraviolet C and He-Ne laser irradiation

作　　者：秦洪云[1] 王书友[1] 束国防[2] 

机构地区：[1]南京铁道医学院附属医院康复科,210009 [2]南京铁道医学院附属医院检验科,210009

出　　处：《中华理疗杂志》2000年第1期29-32,共4页Chinese Journal of Physical Therapy

摘　　要：目的　研究短波紫外线（ＵＶＣ）与氦氖激光照射对感染性伤口愈合作用的影响，并判别其作用的差异性。方法　将５０ 只Ｈａｒｔｌｅｙ 豚鼠随机分为３ 组：ＵＶＣ组、激光组各２０ 只，对照组１０ 只（不做特殊处理） 。首先在豚鼠背部造成实验性感染伤口，感染４８ ｈ 后进行治疗，每天１ 次，９ 次为１ 疗程。并在治疗前、治疗３，６，９ ｄ 后分别对感染伤口的变化进行观察；抽取眼静脉血检查白细胞计数及切取皮肤组织标本进行光镜与电镜分析。结果　ＵＶＣ组与激光组各项指标明显优于对照组，伤口炎症浸润的缩小率，治疗３ ｄ 后ＵＶＣ 组（６０．４５ ±１ ．８７） ％ ，激光组（３３ ．９６ ±１ ．４４） ％ ，对照组（１０．１８±１ ．６５）％ 。ＵＶＣ 组与激光组、对照组比较，χ２ ＝ ９ ．５８，１２．６１，Ｐ＜ ０ ．０１ ，差异均有非常显著性，而ＵＶＣ组又优于激光组。结论　ＵＶＣ 与激光对感染性伤口的愈合均有良好的促进作用，其中ＵＶＣ效果更佳。Objective To study the healing effect of ultraviolet C(UVC) and He-Ne laser irradiation on the infected wound and distinguish the effect of UVC from He-Ne laser.Methods 50 Hertley quinea-pigs were artificially formed the infected wound on back of quinea-pig,and were randomly divided into UVC group,laser group and contrast group(without any special treatment).After 48 hours of infection,the UVC or He-Ne laser was given,once a day,for 9 times.Before and after the 3rd,6th,9th day of treatment,the alteration of infected wound was observed,the WBC of eye venous blood was detected and the incised skin tissue was histopathologically analysed by light and electron microscope.Results The healing effects of UVC and laser group were all better than the contrast group.The effect of UVC was superior to the laser.Conclusion The study demonstrates that both UVC and He-Ne laser have the effect to promote the healing of infected wound,especially the result of UVC is better.

关 键 词：紫外线 伤口感染 UVC 氦氖激光 光疗法 

分 类 号：R640.5[医药卫生—外科学] R454.2[医药卫生—临床医学]