2010年广东省深圳市病毒性腹泻监测结果分析  

Surveillance of viral diarrhea in Shenzhen in 2010

作　　者：张海龙[1] 李苑[2] 张克春 杨洪[1] 阳帆[1] 罗敏[1] 冼慧霞[1] 姚相杰[1] 何雅青[1] 

机构地区：[1]深圳市疾病预防控制中心,广东深圳518020 [2]深圳市宝安区疾病预防控制中心 [3]深圳市宝安区福永预防保健所

出　　处：《疾病监测》2012年第1期4-7,共4页Disease Surveillance

基　　金：2011年深圳市科技计划项目(No.201102104);2011年深圳市宝安区科技创新局资助项目(No.20110597)~~

摘　　要：目的了解广东省深圳市病毒性腹泻的感染情况。方法采用实时荧光定量-聚合酶链反应对2010年1-12月深圳市925例疑似腹泻患者粪便标本同时进行轮状病毒、诺如病毒、星状病毒和肠道腺病毒核酸检测。结果 4种常见腹泻病毒的检出率分别为25.30%、20.11%、1.51%和2.27%。轮状病毒和诺如病毒全年各月均维持较高的检出率;轮状病毒感染有明显的季节特征,秋冬季为发病高峰;诺如病毒感染则无特殊的季节特征。0～2岁年龄组患者的感染率显著高于3岁以上年龄组患者。结论 2010年深圳市病毒性腹泻呈高发状态,其中轮状病毒和诺如病毒是主要的病原之一,星状病毒与肠道腺病毒的检出率较低。应加强对病毒性腹泻,尤其是婴幼儿病毒性腹泻的监测。Objective To understand the incidence of viral diarrhea in Shenzhen in 2010 and provide evidence for the prevention and treatment of the disease.Methods A total of 925 stool samples were collected from diarrhea patients to detect rotavirus,norovirus,astrovirus and enteric adenovirus by using real-time polymerase chain reaction（real-time PCR）.Results The detection rate of rotavirus was highest（25.30%）,followed by norovirus（20.11%）,enteric adenovirus（2.27%）,and astrovirus（1.51%）.The detection rates of rotavirus and norovirus were high in every month in 2010.The rotavirus infection had obvious seasonality,which peaked in autumn and winter,while the norovirus infection had no obvious seasonality.The infection rates in age group of 0-2 years were significantly higher than those in age groups of 3 years.Conclusion The incidence of viral diarrhea was high in Shenzhen in 2010.Rotavirus and norovirus were the major pathogens.The detection rates of astrovirus and enteric adenovirus were low.It is necessary to strengthen the surveillance of viral diarrhea,especially among infants and young children.

关 键 词：病毒性腹泻 轮状病毒 诺如病毒 星状病毒 肠道腺病毒 

分 类 号：R725.1[医药卫生—儿科]