大孔树脂技术在中药提取纯化中的应用及展望  

Application and Prospect of Macroporous Resin Technology in Extraction and Purification of Traditional Chinese Medicine

作　　者：张旭[1,2] 王锦玉[1] 仝燕[1] 李艳玲[1,2] 马振山[1] 王琳[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]天津中医药大学,天津300073

出　　处：《中国实验方剂学杂志》2012年第6期286-290,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家"重大新药创制专项"课题(2009ZX09301-005)

摘　　要：对近10年大孔树脂技术在中药方面的应用文献进行整理和归类分析,其中包括中药单、复方中有效成分的分离精制、中药有害杂质的脱除、树脂中有机残留的控制、大孔树脂再生等;并对大孔吸附树脂技术的应用领域扩展进行探讨。大孔吸附树脂分离技术主要应用于皂苷、黄酮、生物碱等成分的富集上,近年来用于重金属杂质和农药残留物脱除。根据中药化合物的结构类型开发研制高选择性的树脂,提高中药有效成分分离效率,快捷、省时、低成本将成为新的发展趋势。选用2009～2011年的参考文献31篇,占总参考文献62%,以期为大孔树脂技术的研究及生产提供参考。This paper was to arrange and classific analyze literature of macroporous resin technology in application for traditional Chinese medicine （TCM） , Including separation and purification of active ingredients from single or compound prescription of TCM, removal of harmful impurities from TCM, conformity organic residues in resin, regeneration of macroporous resin and so on. And to investigate expansion of application field of macroporous resin technology. Separation technology of macroporous resin was mainly used in enrichment of saponins, flavonoids, alkaloids and so on, but in recent years, it was used in removal of heavy metal impurities and pesticide residues. According to structure type of TCM compound, to develop high selectivity of resin, separation efficiency of active ingredients from TCM was improved, in the future, fast, time-saving, low cost will be new trend. 31 articles were selected which published in 2009-2011 years, these articles took up more than 62% of total references, hope for providing reference for research and production of macroporous resin technology.

关 键 词：大孔吸附树脂 中药 提取纯化 

分 类 号：R283.6[医药卫生—中药学]