新疆乌鲁木齐地区维吾尔族健康人群骨矿含量DXA测量分析  

The analysis of bone mineral density measured with DXA in health Uygur dwellings in Urumqi

作　　者：刘德浩[1] 李白艳[2] 张鹏[2] 

机构地区：[1]厦门大学附属第一医院放射科,厦门361003 [2]新疆医科大学第一附属医院影像中心

出　　处：《中国骨质疏松杂志》2012年第2期118-122,126,共6页Chinese Journal of Osteoporosis

摘　　要：目的通过测量乌鲁木齐市1485人维吾尔族健康人群的骨密度(BMD),确定本市BMD正常参考值,并探讨BMD随年龄变化的规律。方法使用法国DMS公司生产的Lexxos型双能X线骨密度仪(Dual-energy X-ray absorptiometer,DXA)对乌鲁木齐市20岁以上的维吾尔族健康人腰椎前后位、左侧股骨近端的BMD进行测定。按不同性别每5岁分为1年龄组,得出BMD值、标准差及累计丢失百分率。结果男性及女性腰椎骨峰值年龄段组均出现在35～39岁组,而股骨近端男性及女性骨峰值年龄段组均出现在20～24岁组,峰值后随年龄增加而骨密度下降,女性在50～74岁呈加速下降趋势,而男性无明显加速下降现象。结论达到骨峰值后BMD随年龄增加而下降,女性绝经后骨量丢失明显加快,男性下降缓慢,女性骨质疏松发病率高于男性。提示预防和治疗骨质疏松的重点在中老年女性,同时老年男性也不容忽视。因此建立本地区健康维吾尔族人群骨峰值及诊断参考值,对于临床诊断早期原发性骨质疏松症有着重要参考意义。Objective To establish the normal reference values of bone mineral density through measuring the bone mineral density of 1485 healthy Uygur dwellings in Urumqi,and to explore the variation rule of BMD alone with age.Methods The BMD of anteroposterior position of lumbar and left proximal femur was measured with DMS Lexxos dual emengy X-ray absorptiometer（DXA） in health Uygur dwellings over 20 years old in Urumqi.These subjects were divided into different groups according to the gender and age（5 years as one age group）.The value of BMD,standard deviation（SD）,and the percent of accumulative loss were obtained.Results The BMD peak values of anteroposterior position of lumbar happened in the 35-39 years old group both in males and females.However,the BMD peak value of proximal femur happened in the 20-24 years old groups of both males and females.BMD decreased along with age after the peak value.The accelerating decrease trend in females happened in the 50-74 years old group and no accelerating decrease trend happened in males.Conclusion BMD decreases along with age after the peak value.The bone loss of postmenopausal women significantly accelerates and the bone loss of males comparatively slow.The prevalence of osteoporosis in females is higher than that in males.This indicates that the prevention and treatment of osteoporosis are very important to the elderly-and middle-aged females but should not be ignored in males.Therefore,the establishment of BMD peak value and reference value database has very important meaning for the diagnosis of primary osteoporosis in early stage in the healthy Uighur population in Urumqi.

关 键 词：骨密度 骨峰值 骨质疏松症 维吾尔族 

分 类 号：R814[医药卫生—影像医学与核医学]