骨代谢相关因子研究进展  

Research progress on bone metaboliam-related factors

作　　者：周建[1] 陈克明[1] 王嘉琪[1] 程国政[1] 

机构地区：[1]兰州军区兰州总医院骨科研究所,兰州730050

出　　处：《中国骨质疏松杂志》2012年第2期175-178,共4页Chinese Journal of Osteoporosis

基　　金：甘肃省科技重大专项资助项目(09ZNKDA025)

摘　　要：骨质疏松症是老年人的一种常见病和多发病,在发病过程受到多个骨代谢相关因子的调控。对骨代谢相关因子进行研究可为骨质疏松症研究预防和治疗提供理论依据。其中骨保护素(Osteoprotegerin,OPG)、骨形态发生蛋白(Bone morphogenetic proteins,BMP)、成纤维细胞生长因子(Fibroblast growth factors,FGF)是近年来研究热点。本文对它们的分子结构以及生物学功能做一综述。Osteoporosis is a common disease in elderly-aged population.The process of osteoporosis is regulated by many bone metabolism-related factors.The research on these factors can provide a theoretic basis for the prevention and treatment of osteoporosis.Osteoprotegerin（OPG）,bone morphogenetic proteins（BMP）,and fibroblast growth factors（FGF） are recent research focuses.This paper reviews their molecular structures and biology functions.

关 键 词：OPG BMP FGF 

分 类 号：R244[医药卫生—针灸推拿学]