磁石炮制前后的理化分析  

Physical and chemical analysis in Magnetitum before and after processing

作　　者：傅兴圣[1] 刘训红[1] 田金改[2] 林瑞超[2] 吴德康[1] 刘圣金[1] 许虎[1] 周逸芝[1] 

机构地区：[1]南京中医药大学,南京210046,[2]中国食品药品检定研究院,北京100050

出　　处：《药物分析杂志》2012年第3期483-487,共5页Chinese Journal of Pharmaceutical Analysis

基　　金：国家十一五科技支撑计划项目:矿物药中金属含量检测技术的研究(2006BAI55B02)

摘　　要：目的:系统分析磁石炮制前后的理化变化。方法:采用性状鉴别、化学滴定法、原子吸收分光光度法(AAS)、原子荧光分光光度法(AFS)和电感耦合等离子发射光谱-质谱法、X射线衍射(XRD)法及差示热重法等分析方法,从性状、元素、物相、热性质等角度系统分析磁石炮制前后的理化变化。结果:磁石经炮制,性状变化显著;全铁量变化不明显,水溶性铁元素溶出增加;重金属及有害元素总量减少,水溶性重金属及有害元素的溶出率下降;新增了氧化铁的物相;热性质变化较大。结论:本实验为阐述磁石炮制增效减毒的科学内涵奠定基础。Objective：The purpose of this paper is to systematically analyzing the physical and chemical change in magnetitum before and after processing.Method： Diagnostic character,chemical titration,atomic absorption spectrometry（AAS）,atomic fluorescence spectrometry（AFS）,inductively coupled plasma emission spectrometry-mass spectrometry（ICP-MS）,X-ray diffraction and differential thermogravimetry and else methods were used for the analysis.Results：By processing,the traits of magnetitum have undergone significant changed but the total iron content did not.The water-soluble iron dissolution increased,on the contrary,the total and water-soluble heavy metals and toxic elements decreased.And after processing,a new phase Fe2O3 created and the thermal property has changed significantly.Conclusion：This paper lays the foundation for describing the scientific content of processing efficiency to magnetitum.

关 键 词：矿物药 磁石 四氧化三铁 炮制 理化变化 性状分析 元素分析 物相分析 热性质分析 增效减毒 

分 类 号：R917[医药卫生—药物分析学]