泌尿系统感染病原菌及药物敏感性分析  

Pathogens causing urinary system infections and drug susceptibility

作　　者：徐力[1] 陈文莉[1] 

机构地区：[1]武汉市中心医院肾内科,湖北武汉430014

出　　处：《中华医院感染学杂志》2012年第5期1058-1059,1071,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解泌尿系统感染病原菌分布及药物敏感性,为临床合理使用抗菌药物提供指导。方法对2010年5月-2011年5月共201例住院患者中段尿培养阳性的病原菌分布及对抗菌药物敏感性进行分析。结果引起泌尿系统感染病原菌共222株,前3位依次为大肠埃希菌占38.7%、变形菌属占12.6%、屎肠球菌占9.5%;大肠埃希菌对亚胺培南、阿米卡星、头孢哌酮/舒巴坦、阿莫西林/克拉维酸的敏感率分别为98.7%、96.2%、96.2%、88.3%;变形菌属对头孢哌酮/舒巴坦、亚胺培南、美罗培南的敏感率分别为100.0%、100.0%、90.0%;屎肠球菌对万古霉素、青霉素的敏感率均为92.3%。结论依照泌尿系统感染病原菌的培养及耐药检测结果,可指导临床上正确合理使用抗菌药物,尽量避免二重感染发生以及耐药菌株的产生。OBJECTIVE To understand the distribution and drug sensitivity of pathogens in urinary system infection so as to guide the reasonable use of antibiotics.METHODS The bacterial culture and susceptibility testing were performed for the isolates from mid-stream urine specimens from 2010 to 2011.RESULTS Among 222 isolates of pathogenic bacteria,the top isolates were Escherichia coli（38.7%）,Proteus（12.6%）,Enterococcus faecium（9.5%）.E.coli was susceptible to imipenem,amikacin,cefoperazone/sulbactam and amoxicillin/clavulanate potassium.the sensitivity rates were 98.7%,96.2%,96.2%,and 88.3%,respectively.Proteus was susceptible to cefoperazone/sulbactam,imipenem,meropenem,the sensitivity rates were 100.0%,100.0%,90.0%,respectively.E.faecium was susceptible to vancomycin,penicillin,the sensitivity rates of E.faecium to vancomylin and penicillin were all 92.3%.CONCLUSION It is important that the clinician use antibiotics reasonably and reduce the rate of double infections and drug resistant strains according to the bacterial culture and susceptibility testing results.

关 键 词：泌尿系感染 病原菌 抗菌药物 敏感性 

分 类 号：R378[医药卫生—病原生物学]