混酸催化1,4-桉叶素异构化合成4-松油醇的研究  

Synthesis of 4-terpineol from isomerization of 1,4-cineole catalyzed by mixed acid

作　　者：项小燕[1] 林锡煌[2] 吴粦华[1] 拓宏桂[1] 

机构地区：[1]龙岩学院化学与材料系,福建龙岩364000 [2]国家海洋局第三海洋研究所,福建厦门361005

出　　处：《应用化工》2012年第2期252-255,共4页Applied Chemical Industry

基　　金：福建省教育厅B类项目资助(JB09220)

摘　　要：研究了在磷酸和乙酸混酸催化下,1,4-桉叶素异构化合成4-松油醇。考察了混酸催化剂种类、催化剂用量、反应温度、反应时间等因素对反应的影响。结果表明,最佳反应条件为:1,4-桉叶素10 mL,在12 mL磷酸与乙酸体积比为6∶1的混合酸催化剂中,反应温度60℃,反应时间8 h,1,4-桉叶素转化率可达74.66%,选择性为75.4%。精制后的4-松油醇质量分数在90%以上。Synthesis of 4-terpineol from isomerization of 1,4-cineole catalyzed by mixed acid was investigated.Effects of types of catalyst,proportion of mixed acid,reaction temperature,reaction time on isomerization of 1,4-cineole were studied.The results indicated that the optimum reaction conditions were as follows：the amount of 1,4-cineole 10 mL,12 mL mixed acid with the volume ratio of phosphoric acid to acetic acid as 1∶2,the temperature 60 ℃,time 8 h.The conversion rate and selectivity was up to 74.66%,75.4%,respectively.The mass content of purified 4-terpineol was over 90%.

关 键 词：1 4-桉叶素 混酸 4-松油醇 异构化 

分 类 号：TQ351.472[化学工程]