血管内径追踪和矢量应变技术评价糖尿病患者颈总动脉弹性的价值  

Value of blood vessel diameter tracking and X-strain technique in evaluating the carotid arterial elasticity in patients with diabetes

作　　者：周玲[1] 张莉[1] 段云友[1] 刘禧[1] 许磊[1] 杨勇[1] 金京兰[1] 曹铁生[1] 

机构地区：[1]第四军医大学唐都医院超声科,西安710038

出　　处：《中华超声影像学杂志》2012年第3期197-200,共4页Chinese Journal of Ultrasonography

摘　　要：目的探讨血管内径追踪和矢量应变技术在评价颈总动脉血管弹性中的价值。方法病例组选择单纯糖尿病患者38例，与病例组年龄、性别匹配的健康志愿者37例作为对照组。应用血管内径追踪和矢量应变技术测量颈总动脉弹性指标：脉搏波传导速度（PWV）、顺应性系数（CC）、僵硬指数（G），内膜环向应变、应变率、应变时间，外膜环向应变、应变率、应变时间，径向应变、应变率、应变时间。分析两组间参数的显著性差异及相关性。结果糖尿病组颈总动脉PWV、β较对照组显著增高（P〈0．05），CC较对照组明显减低（P〈0．05）；内外膜环向应变、应变率和径向应变、应变率指标较对照组显著减低（P〈0．05），相对应的应变时间较对照组延长（P〈0．05）；两组间纵向应变指标差异无统计学意义。糖尿病组CC与PWV呈显著负相关（r=-0．872，P〈0．001），年龄、收缩压、8与PWV正相关（分别r=0．322，P=0．005；r=0．384，P=0．001；r=0．927，P〈0．001）。结论血管内径追踪技术所测量的硬度及顺应性指标和矢量应变技术所获得的环向及径向应变指标能够直观地反映糖尿病患者血管弹性的变化。Objective To investigate the clinical value of blood vessel diameter tracking and X strain technology in evaluating the carotid elasticity in patients with diabetes. Methods Thirty-eight patients who were confirmed as diabetes without complications were enrolled in this study as the patient group and thirtyseven healthy volunteers matched with the patient group with sex, ages were typed as controls. The parameters reflecting common carotid elasticity： pulse wave velocity （PWV）, compliance coefficient （CC）, stiffness index（β）, endovascular circumferential strain, strain rate, strain time （EN CS, EN_ CS_ T, EN_CSR, EN_ CSR_ T）, adventitial circumferential strain, strain rate, strain time （ EP_ CS, EP_ CS_ T, EP_CSR, EP_ CSR_ T）, radial strain （RS） , radial strain rate （RSR） and radial strain time （ RST ） were measured using blood vessel diameter tracking technique and X-strain technique. Significant difference between the two groups and correlations among these variables were evaluated. Results In patient group, PWV and β were significantly higher than those of the control group, while variables like CC, EN_CS, EN_CSR,EP_CS, EP_CSR, RS and RSR were lower with P 〈0.05. All strain time prolonged in patient group （ P〈0.05）. No significant differences were observed in longitudinal strain index. Furthermore, CC was inversely related with PWV（ r = - 0. 872, P 〈0. 001 ）, and age, systolic pressure, 13 were positively related withPWV （r =0.322, P = 0.005; r = 0.384, P = 0.001; r = 0.927, P 〈0.001） in patients group. Conclusions The stiffness and compliance indexes measured by blood vessel diameter tracking technique and the circumferential and radial strain index obtained by X-strain technique can reflect vessel elasticity change of patient with diabetes objectively.

关 键 词：超声检查 糖尿病 颈总动脉 弹性 

分 类 号：R445.1[医药卫生—影像医学与核医学]