双绒毛膜囊双胎早孕期发育不均衡性的超声研究  

Fetal discrepancy during first trimester in dichorionic twins

作　　者：张一休[1] 孟华[1] 欧阳云淑[1] 姜玉新[1] 戴晴[1] 徐钟慧[1] 杨萌[1] 袁岩[1] 鲁嘉[1] 楼海亚[1] 李鹏[1] 杨筱[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院超声科,北京100730

出　　处：《中华超声影像学杂志》2012年第3期228-230,共3页Chinese Journal of Ultrasonography

基　　金：基金项目：国家科技支撑计划“重大出生缺陷和遗传病的防治研究一严重胎儿结构异常影像学产前筛查和诊断新技术的研究”资助项目

摘　　要：目的研究正常双绒毛膜囊双胎在早孕期发育不均衡性的发生率及其统计学分布。方法对66例正常双绒毛膜囊双胎进行早孕期超声检查，测量每个胎儿的头臀长、颈项透明层厚度（NT）、心率、最大羊水深度，计算双胎间上述超声指标的差值和比值。对所有双胎妊娠随访至出生后1个月，评价正常双绒毛膜囊双胎妊娠早孕期发育不均衡性的发生率。结果早孕期双胎中大、小胎儿的头臀长、NT、心率及羊水深度的差异具有统计学意义（P〈0．001）。结论双胎间生长发育在早孕期即存在不均衡性。Objective To investigate the incidence and distribution of fetal discrepancy during the first trimester in dichorionic twins. Methods This was a prospective analysis of dichorionic twin pregnancies that underwent 11＋0 - 13＋6 week scan at a tertiary hospital from Sep 2008 to Oct 2010. Differences in crown-rump length （CRL）, nuchal translucency （NT）, heart rate （HR）, deepest vertical pockets of amniotic fluid （DVP） for every pair of twin fetuses were calculated and expressed as absolute value and percentage of discordance. Results A total of 66 dichorionic twin pregnancies were included. The average CRL was significantly different between the larger fetus and the smaller one,which were （65.28 ± 8.54）mm and （62.34± 8.49）mm respectively （P 〈0. 001）. The average NT was significantly different between two fetuses,which were （1.56± 0.35）mm and （1.28 ± 0.30）mm respectively. HR and DVP were also statistically different between two fetuses （ P 〈0. 001）. Conclusions The growth of two fetuses in normal dichorionic twins is not uniform during the first trimester.

关 键 词：超声检查 双生 二卵 妊娠初期 发育不均衡性 

分 类 号：R445.1[医药卫生—影像医学与核医学]