An evolving picture of the interactions between malaria parasites and their host erythrocytes  

An evolving picture of the interactions between malaria parasites and their host erythrocytes

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作  者:Thomas E Wellems Rick M Fairhurst 

机构地区:[1]Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health,Bethesda, Maryland20892-8132, USA

出  处:《Cell Research》2012年第3期453-456,共4页细胞研究(英文版)

摘  要:In patients with malaria, Plasmodium falciparum parasites multiply to enormous numbers in the bloodstream, initiating processes of erythrocyte destruction, endothelial activation and microvascular inflammation that cause devastating pathological effects on host tissues and organs. Recent research casts new light on a mechanism by which hemoglobin mutations may protect against these effects, and on a critical receptor-ligand interaction that provides fresh opportunities for the development of vaccines against blood-stage infection.

关 键 词:相互作用 红细胞 寄生虫 疟疾 图片 演变 宿主 繁殖数量 

分 类 号:Q592.1[生物学—生物化学] S858.265.9[农业科学—临床兽医学]

 

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