彩色多普勒血流检测对原发性肾病综合征并肾间质损害的评估价值  

THE VALUE OF COLOR DOPPLER FLOW MEASUREMENT IN THE ASSESSMENT OF PATIENTS WITH PRIMARY NEPHROTIC SYNDROME COMPLICATING RENAL INTERSTITIAL DAMAGE

作　　者：于宁[1] 禹静[1] 杨雪[1] 

机构地区：[1]青岛大学医学院附属医院超声科,山东青岛266003

出　　处：《青岛大学医学院学报》2012年第1期36-38,共3页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：目的了解肾脏彩色多普勒血流检测对原发性肾病综合征并肾间质损害的评估价值。方法将51例原发性肾病综合征病人根据肾间质损害程度分为轻度损害组、中度损害组、重度损害组,25例健康对照者作为对照组;检测所有受检者肾脏段动脉(SRA)、叶间动脉(IRA)血流参数。结果中度损害组肾IRA舒张末期最低血流速度(Vmin)减慢、阻力指数(RI)增高,与对照组及轻度损害组比较差异有显著性(F=5.70～15.10,q=4.49～5.67,P<0.05);重度损害组与其他组比较肾脏各级动脉最大血血流速度度、最小血血流速度度明显减慢,RI明显增高,差异有显著性(q=2.88～7.64,P<0.05)。结论肾间质损害程度是影响原发性肾病综合征治疗效果及预后的重要因素,肾脏彩色多普勒血流检测能够反映肾间质损害的严重程度,有助于判断原发性肾病综合征病人病情及预后。Objective To investigate the value of color Doppler flow measurement in evaluation of primary nephrotic syndrome（PNS） complicating renal interstitial impairment.Methods Fifty-one PNS patients,according to the degree of impairment of renal interstitium,were divided into mild-moderate-and severe-damage groups,and 25 healthy individuals served as controls.The blood stream parameters of segmental renal artery（SRA） and interlobar artery（IRA） were tested in all subjects.Results In moderate-damage group,end-diastolic velocity（Vmin） of IRA stepped down,and the resistance index（RI） elevated,the differences were significant versus that in the control and mild-damage groups（F=5.70-15.10,q=4.49-5.67,P〈0.05）;the differences between severe-damage group and other groups were significant in terms of decreased peak velocity in systole and the end-diastolic velocity,and increased pulsed index（q=2.88-7.64,P〈0.05）.Conclusion The extent of renal interstitial impairment is an important factor that influences the therapeutic efficacy and prognosis of PNS.Color Doppler renal blood flow measurement can reflect the degree of impairment of renal interstitium,which is conducive to judgement of the condition of the patients and their prognosis.

关 键 词：超声检查 多普勒 彩色 肾病综合征 肾炎 间质性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R692.3[医药卫生—诊断学]