艾滋病合并马尔尼菲青霉病83例的胸部影像表现分析  被引量:6

Analysis of Chest Imaging in 83 AIDS Patients Complicated with Penicillium Marneffei

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作  者:卢祥婵[1] 秦英梅[1] 黄爱春[1] 黎之利[2] 卢亦波[2] 

机构地区:[1]广西南宁市第四人民医院感染科,南宁市530023 [2]广西南宁市第四人民医院放射科,南宁市530023

出  处:《广西医学》2012年第2期154-157,共4页Guangxi Medical Journal

基  金:国家科技重大专项(2008ZX10001-008);广西医疗卫生科研课题(桂卫Z2010158);广西南宁市科学研究与技术开发计划项目(201003047C-1;201003047C-2)

摘  要:目的探讨获得性免疫缺陷综合征(AIDS)合并马尔尼菲青霉病(青霉病)的胸部影像表现及治疗后转归。方法对83例艾滋病合并青霉病患者的胸部影像表现及临床资料进行回顾性分析。结果 83例患者胸部X线、CT影像学表现主要为5种类型:(1)以结节病变为主要表现29例;(2)以斑片或大片状渗出为主要改变27例;(3)以肿块病变表现6例;(4)双肺呈弥漫磨玻璃样改变为主5例;(5)双肺呈弥漫粟粒病变5例;(6)其他表现11例。治疗后肺部病灶明显吸收、消失77例,死亡6例。病灶呈双肺弥漫分布的患者病死率为14.6%(6/41),高于其他病灶分布患者(0/42),差异有统计学意义(P<0.05);CD4+T细胞计数多少与病死率关系不大(P>0.05)。结论青霉病绝大部分发生于AIDS晚期患者,胸部表现多种多样,以双肺弥漫性病变患者病死率高。To investigate the chest imaging and treatment outcome of AIDS patients complicated with Penicillium marneffei (PM). Methods The chest imaging and clinical data of 83 AIDS patients complicated with PM were analyzed retrospectively. Results There were five types of the chest CT and Xray imaging in these 83 patients:( 1 )nodules as main performance in 29 cases; (2)Patch or big shape exudation in 27 cases;(3)Masses lesions in 6 cases; (4)Diffuse groundglass shadows in 5 cases of bilateral lungs; (5)Diffuse miliary lesions of bilateral lungs as main performance in 5 cases ; (6) Other appearances found in 11 cases. The lung lesions of 77 patients were absorbed and disappeared apparently after treatment. Mortality rate of the patients with diffuse lesions distribution of bilateral lungs was 14.63% (6/41) ,which higher than that of the else cases(0/42) ,and there was significant differenee(P 〈0.05) ;The counting of CD4 + T lymphocytes had little relationship with mortality rate (P 〉 0.05). Conclusion Penieillium marneffei mostly appears in late AIDS patients, the chest imaging appearance is multiple, and its mortality rate is high in the patients with diffuse lesions of bilateral lungs.

关 键 词:获得性免疫缺陷综合征 马尔尼菲青霉病 影像学 

分 类 号:R512.91[医药卫生—内科学] R445[医药卫生—临床医学]

 

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