乌鲁木齐市特殊人群麻疹抗体水平分析  

Analysis of measles antibody level of special population in Urumqi

作　　者：巴特尔[1] 刘健[1] 张勇 王君[1] 杨艳梅[1] 严丽 吴亚英[1] 曹琦[1] 谢彦玲 李惠敏 

机构地区：[1]新疆乌鲁木齐市疾病预防控制中心,乌鲁木齐830026 [2]乌鲁木齐市妇幼保健医院,乌鲁木齐830002

出　　处：《疾病预防控制通报》2012年第1期32-34,共3页Bulletin of Disease Control & Prevention(China)

基　　金：乌鲁木齐市卫生局科技计划项目(201007)

摘　　要：目的通过检测乌鲁木齐市育龄期妇女血清麻疹IgG抗体水平,分析近年来成人及婴儿麻疹发病率增加的原因,为育龄期妇女及婴儿麻疹感染提出可行的预防策略。方法对拟孕妇女进行问卷调查、采集静脉血,用酶联免疫吸附法(ELISA)定量检测血清麻疹IgG抗体。结果调查拟孕妇女112名,其中血清抗体阳性率为87.5%,抗体几何平均浓度(GMC)为973.2 mIU/ml。主要以低、中水平为主,分别占42.0%和45.5%;易感水平占12.5%。结论乌鲁木齐市拟孕妇女血清麻疹抗体阳性率较低,使其所生婴儿一出生麻疹抗体水平就达不到保护性水平,成为易感人群;因此,加强此类人群麻疹疫苗的接种,是有效降低8个月龄以内婴儿的麻疹发病率的可行的策略。Objective To determine serum IgG level of measles of child-bearing women and analyze reasons for incidence increase of adults and infants in recent years,so as to propose feasible prevention strategy of measles virus infection for child-bearing women and infants.Methods Women intending to be pregnant were carried out questionnaires and taken blood samples for quantitative detection for serum IgG level by ELISA.Results Positive rate of the serum antibody and GMC were 87.5% and 973.2 mIU/mL,respectively,among the 112 investigated women.It was mainly low and intermediate level,accounted for 42.0% and 45.5%,respectively.Susceptible level occupied 12.5%.Conclusions The positive rate of serum measles antibody is low in women intending to be pregnant.It makes measles antibody of infants to be born under protection level,and they become susceptible population.Therefore,it is a feasible strategy to strengthen measles vaccine inoculation in the population,in order to effectively decrease measles incidence rate in 8-month-old infants.

关 键 词：特殊人群 抗体水平 麻疹 分析 

分 类 号：R511.1[医药卫生—内科学] R181.81[医药卫生—临床医学]