89株术中留取胆汁需氧菌培养病原菌种类及耐药分析  

Analysis of drug resistance and bacteria culture for 89 strains of bile aerobe pathogenic fungi

作　　者：徐涛 陈玉莲 翁杏花 邢孔鸯 李磊邦 

机构地区：[1]广东省台山市人民医院检验科,529200

出　　处：《检验医学与临床》2012年第6期649-650,652,共3页Laboratory Medicine and Clinic

摘　　要：目的了解胆汁细菌学培养的病原菌分布及耐药情况,为个体化及经验用药提供科学依据,指导临床合理使用抗菌药物。方法对89株术中留取胆汁进行需氧菌培养,用法国生物梅里埃公司ATB Expression自动细菌鉴定仪进行鉴定、药敏测定。结果 2009年1月至2011年10月共分离出病原菌89株,其中革兰阳性球菌48株,占53.9%,革兰阴性杆菌39株,占43.9%,真菌2株,占2.2%;药敏结果显示革兰阳性球菌对替考拉宁、万古霉素敏感性高,革兰阴性杆菌对亚胺培南、美罗培南敏感性高,对临床胆道细菌感染常用的第三代头孢菌素耐药率已达33%～50%。结论该地区胆道感染的致病菌第一位是粪肠球菌或粪肠球菌和大肠埃希菌混合感染,在常规经验抗感染的治疗中应兼顾到肠球菌。Objective To understand the distribution of bile bacteriological culture and drug resistance of pathogenic bacteria,and to provide scientific bases for experience and individual clinical medications of antibiotics.Methods 89 patients＇ bile simples were obtained for aerobic bacterial culture by France bioMerieux ATB Expression automatic bacterial identification instrument for identification,drug susceptibility determination.Results From January 2009 to October 2011,89 strains of pathogens were totally isolated,48（53.9 %）strains were gram positive coccus,39（43.9%） strains were gram negative bacilli,and 2（2.2%） strains were fungi.Gram positive coccus had high sensitivity to teicoplanin and vancomycin.Gram negative bacilli had high sensitivity to imipenem and meropenem.Resistance rate of biliary tract bacterial infection to third-generation cephalosporin antibiotic was from 33% to 50 %.Conclusion This local biliary duct infects pathogenic bacteria infection rates of excrement enterococcus and the excrement enterococcus mixed with E.coli are highest in biliary tract infection.It is necessary to consider about excrement enterococcus in experience treatment of anti-infection.

关 键 词：胆道感染 胆汁培养 细菌 耐药性 

分 类 号：R181.34[医药卫生—流行病学]