先天性梅毒的早期临床及骨骼X线特征  

Early Clinical Manifestations and Skeletal X-ray Findings of Congenital Syphilis

作　　者：张桂艳[1] 刘锟[1] 何家维[1] 严志汉[1] 

机构地区：[1]温州医学院附属第二医院放射科,325000

出　　处：《医学研究杂志》2012年第2期165-168,共4页Journal of Medical Research

摘　　要：目的探讨先天性梅毒的早期临床及骨骼X线特征。方法回顾性分析75例确诊为先天性梅毒的临床及X线特征,所有患儿均有骨骼系统X线检查,其中男性43例,女性32例,年龄4h～6个月,平均年龄21天。结果 75例患儿中,13例无明显临床症状;62例有不同临床症状,其中43例累及皮肤、黏膜,25例累及肺及肝脏等内脏器官,7例有肢体活动障碍或肿胀。15例骨骼系统有异常改变,主要包括干骺端软骨炎12例,骨膜炎6例,骨干炎5例。结论先天性梅毒临床表现多样,及时的实验室检查和骨骼系统X检查有助于早期诊断。Objective To investigate early clinical manifestations and skeletal X-ray findings of congenital syphilis.Methods The clinical manifestations and X-ray findings of 75 cases（22 female,53 male;mean age of 21 days;age range of 4h-6m）with confirmed congenital syphilis were retrospectively analyzed.Results Of the 75 patients,13 had normal clinical manifestations,and 62 had abnormal clinical manifestations involved multiple systems,with the skin and mucous membrane involved in 43 cases,with lung,liver and other visceral involved in 25cases,with extremities obstacle or swelling in 7cases.15 cases had abnormal skeletal X-ray findings,which included osteochondritis in the metaphysis（n=12）,periostitis（n=6）,and diaphysitis（n=5）.Conclusion Clinical manifestations of congenital syphilis in the neonates are variable.Real-time laboratory examination combined with bone X-ray examination are helpful for early diagnosis of the congenital syphilis in neonate.

关 键 词：先天性梅毒 临床 骨骼 X线 

分 类 号：R759.15[医药卫生—皮肤病学与性病学]