Genetic diversity analysis of Penicillium marneffei isolated from AIDS patients in Guangdong, China using randomly amplified polymorphic DNA  

作　　者：LI Ling-hua HU Feng-yu CHEN Wan-shan CAI Wei-ping SONG Wei-nan KUANG Yan-ling TANG Xiao-ping 

机构地区：[1]Department of Infectious Diseasesand Guangzhou No. 8 People＇s Hospital, Guangzhou,Guangdong 510060, China [2]Institutefor Infectious DiseasesandGuangzhou No. 8 People＇s Hospital, Guangzhou,Guangdong 510060, China

出　　处：《Chinese Medical Journal》2012年第5期823-827,共5页中华医学杂志（英文版）

基　　金：This work was supported by the grants from the Key Subject Programs of Guangzhou Municipal Health Bureau （No. 2009-Zdi-16）; the Natural Science Foundation of Guangdong Province （No. 10151006002000000）; and Chinese National llth Five-year Plan on Key Infectious diseases （No. 2008ZX10001-006）.

摘　　要：Background Penicillium mameffei （P. marneffe~） is an emerging pathogenic fungus that can cause invasive mycosis in patients with AIDS. The epidemiological features of P. marneffeiinfection in AIDS patients in Guangdong province remain unclear so far. This study aimed to investigate the genetic diversity within a population of 163 P. mameffei isolates obtained from AIDS patients and search for the dominant clinical strains in Guanqdong province.Background Penicillium mameffei （P. marneffe~） is an emerging pathogenic fungus that can cause invasive mycosis in patients with AIDS. The epidemiological features of P. marneffeiinfection in AIDS patients in Guangdong province remain unclear so far. This study aimed to investigate the genetic diversity within a population of 163 P. mameffei isolates obtained from AIDS patients and search for the dominant clinical strains in Guanqdong province.

关 键 词：penicillium marneffei randomly amplified polymorphic DNA acquired immune deficiency syndrome genetic diversity 

分 类 号：S635.1[农业科学—蔬菜学] Q959.468[农业科学—园艺学]