赤雹根乙醇提取物对急性血瘀模型大鼠血液流变学的影响  

EFFECTS OF ALCOHOL EXTRACT OF THLADIANTHA DUBIA ROOTS ON HEMORHEOLOGY OF ACUTE BLOOD STASIS MODEL RATS

作　　者：高冲[1] 李亚洲[1] 刘玉玲[1] 佟继铭[1] 刘永平[1] 

机构地区：[1]河北省中药研究与开发重点实验室承德医学院中药研究所,河北承德067000

出　　处：《承德医学院学报》2012年第1期1-3,共3页Journal of Chengde Medical University

基　　金：河北省自然科学基金项目(C2008000655);河北省教育厅重点项目(2D2010131)

摘　　要：目的:观察赤雹根乙醇提取物(AETR)预处理对急性血瘀模型大鼠血液流变学指标的影响。方法:采用皮下注射盐酸肾上腺素加冰水浴的方法制作大鼠急性血瘀模型,以红细胞压积(HCT)、血沉方程K值、血浆粘度、全血粘度为指标,评价AETR对大鼠血液流变学指标的影响。结果:AETR(1.4g/kg、0.7g/kg、0.35g/kg)各剂量组大鼠的HCT、血沉方程K值、血浆粘度及全血粘度均明显低于模型组(P<0.05,P<0.01)。结论:AETR预处理可明显改善急性血瘀模型大鼠的血液流变学特性。Objective：To observe the effects of alcohol extract of Thladiantha Dubia roots （AETR） pretrealment on hemorheology of acute blood stasis model rats.Methods：The acute blood stasis model rats were established by subcutaneous injection of adrenalin hydrochloride and icewater bath. Hematocrit, equation K value of erythrocyte sedimentation rate, plasma viscosity and whole blood viscosity were used to evaluate the effects of AETR on hemorheology of rats.Results：The hematocrit, equation K value of erythrocyte sedimentation rate, plasma viscosity and whole blood viscosity of rats in each AETR group （1.4g/kg, 0.Tg/kg, 0.35g/kg） were all obviously lower than that of rats in model group （P〈 0.05,P〈 0.01）.Conelusions：AETR pretreatment can obviously improve the hemorheology of acute. blood stasis model rats.

关 键 词：赤雹根 乙醇提取物 急性血瘀模型 血液流变学 

分 类 号：R963[医药卫生—微生物与生化药学]