半枝莲乙醇提取物体外抗氧化活性研究  

The Antioxidant Activity of Ethanol Extract from Scutellariae barbatae

作　　者：廖月霞[1] 王笑娜[1] 孔桂美[1] 赵梁[1] 卜平[1] 

机构地区：[1]扬州大学医学院,江苏扬州225009

出　　处：《时珍国医国药》2012年第3期520-522,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(No.NSFC30873343)

摘　　要：目的分析半枝莲乙醇提取物及不同极性溶剂萃取后体外抗氧化活性。方法乙醇提取半枝莲黄酮类化合物,以石油醚、乙酸乙脂、正丁醇分别萃取得各部分化合物,200～750 nm吸收光谱扫描,进行ABTS+、羟自由基、DPPH自由基清除实验。结果半枝莲乙醇提取物具有明显抗ABTS+、羟自由基、DPPH自由基活性,不同极性溶剂萃取半枝莲黄酮对其抗氧化能力有不同程度影响。结论半枝莲乙醇提取物具有明显抗氧化活性,分类萃取可降低其抗氧化活性。Objective To analyze the antioxidant activity of the extracts from Scutellaria barbata D.Don（S.barbata） with ethanol and different polar solvent. Methods The flavones were segregated from S.barbata with ethanol,and then extracted with ligroin,ethyl acetate,n-butyl alcohol,respectively.Absorption spectrum of the extract was scanned from 200 to 750 nm.ABTS＋,hydroxy radical and DPPH were measured to analyze the antioxidant activity. Results The extract from S.barbata had activities to scavenge ABTS＋,hydroxy radical and DPPH significantly.The extracts from different polar solvent had different antioxidant activities. Conclusion The extract from S.barbata has antioxidant activity.The extracts with different polar solvent respectively can affect the antioxidant activity significantly.

关 键 词：半枝莲 黄酮 ABTS 羟自由基 DPPH 

分 类 号：R285.5[医药卫生—中药学]