C8修饰的胺丙基有序杂化介孔硅胶的制备及其性能研究  

Synthesis and characteraziton of C8-functionalized ordered mesoporous aminopropyl-silica

作　　者：冉瑞雪[1] 狄斌[1,2] 常军民[2] 

机构地区：[1]中国药科大学药物分析教研室,江苏南京210009 [2]新疆医科大学药学院药物分析教研室,乌鲁木齐830011

出　　处：《新疆医科大学学报》2012年第3期315-318,共4页Journal of Xinjiang Medical University

基　　金：国家自然科学基金面上项目(编号:81173022)

摘　　要：目的建立胺丙基杂化介孔硅胶(APMO)表面键合修饰的方法,并对C8修饰的胺丙基介孔硅胶(C8-APMO)进行色谱和吸附性能研究。方法采用共缩聚法制备氨丙基杂化介孔硅胶,后嫁接法对介孔硅胶进行C8修饰,采用元素分析,红外光谱等方法进行表征,吸附和液相方法进行性能测试。结果 C8成功地键合到了AP-MO上,C8-APMO具有大的比表面积(765m2/g)、孔径3.9nm,对苦参素的吸附性能优于商品硅胶,用作色谱固定相,有效分离了3种芳香类化合物苯胺、甲苯和蒽。结论作为吸附和色谱材料,C8-APMO具有较好的应用前景。Objective To establish method of modifying the mesoporous aminopropyl-silica（APMO） with C8 functionality and study the adsorption and separation capacity of the C8-functionalized mesoporous aminopropyl-silica（C8-APMO）.Methods Mesoporous aminopropyl-silica was prepared by co-condensation method,and C8 was introduced to the mesoporous silica via the grafting method.Elemental analysis and IR spectrophotometry were proposed for the characterization of the C8-APMO,and adsorption and LC tests for the performance.Results C8 were successfully bonded onto the surface of APMO.C8-APMO had high surface area（765 m2/g）,pore-size 3.9 nm and stronger adsorption over commercial silica for oxymatrine.The colum with C8-APMO showed good separation capacity of phenylamine,toluene and anthracene.Conclusion C8-APMO has a bright future as the adsorptive and chromatographic materials.

关 键 词：C8 介孔硅胶 吸附 固定相 

分 类 号：R917[医药卫生—药物分析学]