糖尿病患者血浆醛固酮水平与糖尿病肾病及植物神经病变的关系  

Relationship between concentration of serum aldosterone and diabetic nephropathy as well as autonomic neuropathy in patients of diabetese

作　　者：范原[1] 罗尧生[1] 薛元明[1] 崔庆华[1] 张云[1] 

机构地区：[1]云南省第一人民医院内分泌科,昆明650032

出　　处：《中国综合临床》2000年第1期25-26,共2页Clinical Medicine of China

摘　　要：目的分析糖尿病患者血浆醛固酮水平变化与糖尿病肾病及植物神经病变之间的关系。方法测定31例糖尿病患者24小时尿白蛋白、心搏间距、血浆醛固酮水平等。结果血浆醛固酮减低组的糖尿病肾病及植物神经病变的发生率，明显高于血浆醛固酮正常组（P＜0．01）。结论糖尿病肾病及植物神经病变可累及肾-素血管紧张素-醛固酮系统，易造成低醛固酮血症。objective To study the relationship between concentration of serum aldosterone and diabetic nephropathy as well as autonomic neuropathy in patients of diabetics. Methods The concentration of serum aldosterone, angiotensin Ⅰ and angiotension Ⅱ of 31 patients with diabetes were measured by using RIA method. Results The incidence of diabetic nephropathy and autonomic neuropathy in the group presenting low level of serum aldosterone was significantly higher than that in the group with normal level of serum aldosterone (P < 0.01 ). Conclusion Diabetic nephropathy and autonomic neuropathy can affect renin, angiotensin and aldosterone system, and is easy to cause hypoaldosteronemia.

关 键 词：糖尿病 血浆 醛因酮 肾病 植物神经病变 

分 类 号：R587.1[医药卫生—内分泌]