健康老年人腰椎多层螺旋CT骨质密度测量  

MSCT Measurement in Lumbar of Healthy Elderly Population

作　　者：吴爱琴[1] 郑文龙[2] 许崇永[1] 严志汉[1] 代敏[1] 余清[3] 

机构地区：[1]温州医学院附属第二医院,325000 [2]温州市第二人民医院 [3]温州医学院公共卫生学院

出　　处：《医学研究杂志》2012年第3期97-99,共3页Journal of Medical Research

基　　金：温州市科技局资助项目(Y20090154)

摘　　要：目的探讨健康老年人腰椎椎体松质骨CT值测量方法和范围,为多层螺旋CT早期诊断骨质疏松症提供依据。方法 102例60岁以上的健康老年人先行DEXA测量腰椎(L1～L4)和髋部骨密度(BMD)值,然后腰椎多层螺旋CT扫描,每例均取腰3椎体椎弓根层面松质骨按9区法和1区法测量CT值。以DEXA测量BMD值为基础,使用统计学方法比较CT值两种测量结果的差异性,以单侧95%可信区间确定测量指标参考值。结果根据WHO诊断标准,该组病例男性、女性DEXA测量骨密度值均在正常范围内;9区法测量男性、女性CT值为:男性165.4±26.7HU,女性157.7±28.9HU;1区法男性、女性CT值为:男性169.6±27.2HU,女性163.4±29.3HU;两种测量方法CT值均数和标准差无统计学差异。决定采用1区法数据,腰3椎体椎弓根层面松质骨CT值下限为男性124.9HU,女性115.2HU。结论腰椎椎体松质骨的CT值测量是对腰椎骨质密度改变较为敏感的方法,确定健康老年人群腰椎椎体松质骨CT值范围,有望为临床诊断骨质疏松症提供有力的依据。建议男性CT值<120.0HU,女性<110.0HU可诊断为骨质疏松症。Objective To investigate the measurement and the range of CT value in lumbar vertebral cancellous bone of healthy elderly population, in order to provide basis for early diagnosis of osteoporosis in multi - slice spiral CT（ MSCT）. Methods Totally 102 ca- ses of healthy elderly population over 60 years were included in the study. BMD value of lumbar （ L1 - L4 ） and hip were measured by DEXA. All cases performed lumbar MSCT scan. The CT value of cancellous bone in pedical level of lumbar 3 was measured by zone 9 and zone 1 methods. Based on BMD value by DEXA, the difference of two CT value measurement was compared by statistical methods. The normal extent of every variable was determined by unilateral 95% confidence interval. Results According to WHO diagnositic standard, the BMD value of the group by DEXA was within the normal range. The mean and standard deviation of CT value was 165.4± 26.7HU for male, 157.7 ± 28.9 for female by zone 9 method, and 169.6 ± 27.2HU for male, 163.4 ± 29.3HU for female by zone 1 methods. There was no significant difference between two measurement methods at the mean and standard deviation of CT value. By the data of zone 1 methods, the minimum CT value of cancellous bone in pedical level of lumbar 3 was 124.9HU for male and 115.2HU for female. Conclusion The CT measurement value of lumbar vertebral cancellous bone was a sensitive method to detect the change of lumbar BMD. Estab- lishment of CT value range in lumbar vertebral cancellous bone of heahhy elderly population can provide a strong basis for clinical diagnosis of osteoporosis. The diagnosis of osteoporosis can be suggested when the CT value was below 120.0HU for male and 110.0HU for female.

关 键 词：骨密度 腰椎 CT值 体层摄影术 X线计算机 

分 类 号：R683[医药卫生—骨科学]