小儿肺炎病原体检测及分析  

Detection and Analysis of Pathogens in Children with Pneumonia

作　　者：陈娟娟[1] 

机构地区：[1]深圳市第二人民医院儿科,518035

出　　处：《医学研究杂志》2012年第3期142-144,共3页Journal of Medical Research

摘　　要：目的了解小儿肺炎病原菌的感染情况,进一步给临床治疗用药提供依据。方法对72例肺炎痰培养阳性资料进行回顾性分析。结果 72例患儿中≤3岁感染率高于3岁以上儿童;胸片常见支气管肺炎,其次为大叶性肺炎、间质性肺炎;病原菌G-菌占81.94%,依次为鲍曼复合醋酸不动杆菌(33.33%),大肠杆菌(19.44%),肺炎克雷伯菌(13.89%),铜绿假单胞菌(11.11%),臭鼻克雷伯菌(4.17%)。G+菌占18.06%,其中金葡菌占11.11%,肺炎链球菌占6.94%。结论本组数据显示婴幼儿(≤3岁)细菌性肺炎感染率高,胸片以支气管肺炎多见,引起肺部感染的病原菌主要为G-菌,对常用的β-内酰胺类抗生素有不同程度的耐药。G-菌对丁胺卡那、亚胺培南,含β-内酰胺酶抑制剂的哌拉西林他唑巴坦敏感,G+菌对万古霉素、利奈唑烷、庆大霉素、左氧氟沙星敏感。Objective To understand the infection situation of pneumonia pathogens in children for providing the basis for the clinical use of drugs. Methods Retrospective analysis of 72 cases with positive of sputum culture were Performed. Results There were more infections in children less than 3 years. The main radiological photograph was brochial pneumonia, next were lobar pneumonia and intersti- tial pneumonia. The main pathogens were G- bacterium （81.94%） , and the turn were Acinetobacter baumannii （ 33.33% ） , Escherichia coll. （ 19.44% ） ,Klebsiella pneumonia （ 13.89% ） , Pseudomons aeruginosa （ 11.11% ） and K. ozaenenae（4. 17% ）. G~ bacterium were 18.06% , and the turn were Staphyloccocus aureus rosenbach （ 11. 11% ） , Streptococcus pneumonia （ 6.94% ）. Conclusion Children less than 3 years had higher infection rate. Brochial pneumonia was main radiological photograph. Main pathogenic bacterium was G- bacteri- um, in which Acinetobacter baumannii was in the majority. The sensitivity of β- lactams in pneumonia pathogens decreased gradually. G- bacterium were sensitive to amikacin,imipenem, piperacillin/tazobactam, and G＋ bacterium were sensitive to vancomycin ,linezolid, cidno- mycin, levofloxacin.

关 键 词：肺炎 痰培养 小儿 

分 类 号：R725.631[医药卫生—儿科]